Results 31 to 40 of about 506,571 (263)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Analysis of Grinding Flow Field under Minimum Quantity Lubrication Condition

open access: yesApplied Sciences, 2023
The flow field around the grinding wheel prevents grinding fluid from entering the grinding area, which deteriorates machining conditions and reduces the quality of the workpiece. MQL (Minimum Quantity Lubrication) grinding uses compressed gas to improve
Weihua Ni, Zishan Ding, Jian Sun
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Prediction of Intraformational Remaining Oil Distribution Based on Reservoir Heterogeneity: Application to the J-Field

open access: yesAdvances in Civil Engineering, 2021
At high water cut stage, the study of remaining oil distribution in water-flooding reservoir is the basis of implementing potential-tapping measures and enhancing oil recovery.
Jie Zhang   +8 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Controlling fluid adhesion force with electric fields

open access: yesPhysical Review E, 2022
9 pages, 5 ...
Pedro H. A. Anjos   +2 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Field Responsive Fluids - A Review

open access: yesKey Engineering Materials, 2012
Magnetorheological (MR), Electrorheological (ER), and Ferrofluids are considered as a class of smart materials due to their novel behavior under an external stimulus such as a magnetic and electrical field. The behavior of these synthetic fluids offer techniques for achieving efficient heat and mass transfer, damping, drag reduction, wetting ...
Seval Genc, Bora Derin
openaire   +3 more sources

Cosmological perturbations with multiple fluids and fields [PDF]

open access: yesClassical and Quantum Gravity, 2002
19 pages, 6 figures, revised thoroughly; published version in Class.
Hwang, Jai-chan, Noh, Hyerim
openaire   +2 more sources

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