Results 61 to 70 of about 220,072 (264)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Fluid-mechanical and electrical fluctuation forces in colloids [PDF]
Physical Review E, 2006 ReVTeX format, one *.eps ...
Drosdoff, D., Widom, A.
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Performance prediction of air drag brake units for Shinkansen and verification by running test
Nihon Kikai Gakkai ronbunshuThe performance of Air Drag Brake (ADB) units for Shinkansen trains was predicted using wind tunnel experiments and numerical analysis, and running tests were carried out using a test car equipped with a number of ADB units.
Hajime TAKAMI +5 more
doaj +1 more source
Simple prediction method of unstable fluid force in turbine blade row of steam turbine
Nihon Kikai Gakkai ronbunshu, 2016 Unstable fluid force may be induced by rotor blade eccentricity in turbo machinery such as steam turbines. To develop a prediction method for unstable fluid force in turbine blade rows, we calculated the fluid force by using computational fluid dynamics (
Kiyoshi YABATA +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
SIMULATION OF FLUID-STRUCTURE INTERACTIONBASED ON AN IMMERSED-SOLID METHOD [PDF]
Journal of Mechanical Engineering and Sciences, 2013 A new method for studying the interaction between an elastic object and a fluid has been developed. The fluid phase including solid interface is solved by our immersed solid method of body-force type.
Takeo Kajishima , Shintaro Takeuchi
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Design and Simulation of Small-Scale Horizontal-Axis Wind Turbine with Diffuser Effect
MATEC Web of Conferences, 2019 The article presents the results of the investigation of a rotor assembly of a wind turbine with a horizontal axis of rotation. The rotor is equipped with a diffuser which is an integral part of the power generating unit.
Czyż Zbigniew +3 more
doaj +1 more source