Results 231 to 240 of about 335,525 (308)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Navigating the International System for Reporting Serous Fluid Cytopathology in pericardial effusion: A meta-analysis. [PDF]

Cancer Cytopathol
Arshia A, Kalfert D, Kholová I.
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Systematic review of the evidence of cardiac dysfunction and intravenous fluid use among children with severe acute malnutrition and severe dehydration. [PDF]

BMJ Paediatr Open
Narra R, Alberti K, Ciglenecki I, Allen BGS, de Polnay K, Tickell KD.   +5 more
europepmc   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Prognostic Impact of Cumulative Fluid Balance in Critically Ill Patients: A Retrospective Cohort Study. [PDF]

Cureus
Gisca E, Costa S, Magno M, Santos CR, Araújo A.   +4 more
europepmc   +1 more source

The fluid paradox: dissociation between clinical and ultrasound parameters of fluid overload - results of the INCIVEX exploratory study. [PDF]

Anaesthesiol Intensive Ther
Wong A, Cheah K, Papathanakos G, Stefanini F, Zawadka M.   +4 more
europepmc   +1 more source

Guidelines for replacement of a balloon gastrostomy tube in infants and pediatric patients: The American Society for Parenteral and Enteral Nutrition. [PDF]

JPEN J Parenter Enteral Nutr
Lyman B, Berman L, Carr K, Frank C, Guenter P, Kassel R, Kimble J, McGinnis C, Oppedisano S, Paton EA, Rempel G, Wakeman DS, Church DD, Mey JT, Peterson S, McKeever L.   +15 more
europepmc   +1 more source