Results 181 to 190 of about 38,651 (312)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Abiotic synthesis during the interaction of ferrous chloride-rich silicic fluids with marble under high-grade metamorphic conditions. [PDF]

Proc Natl Acad Sci U S A
Fei C, Guo S, Li Y, Liu J.
europepmc   +1 more source

Late Eocene to early Oligocene quantitative paleotemperature record: evidence from continental halite fluid inclusions. [PDF]

Sci Rep, 2014
Zhao YJ, Zhang H, Liu CL, Liu BK, Ma LC, Wang LC.   +5 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Seawater temperature recorded in the last phase of Late Cretaceous in the Yarkand Basin. [PDF]

Sci Rep
Li Y, Wang J, Yang S, Cao Y.
europepmc   +1 more source

Haptic Simulation of Linear Elastic Media with Fluid Inclusions

, 2005
Andrew H. Gosline, Septimiu E. Salcudean, J. Yan   +2 more
openalex   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Onset of slab mantle melting in Earth's lower mantle: Evidence from ferropericlase in superdeep diamonds. [PDF]

Sci Adv
Ni P, Shirey SB, Walter MJ, Czas J, Novella D, Nestola F, Kueter N, Smith EM, Stachel T, Pearson DG, Steele A, Gardner LL, Jacobsen SD, Harte B, Harris JW, Shahar A.   +15 more
europepmc   +1 more source

Acidophilic halophilic microorganisms in fluid inclusions in halite from Lake Magic, Western Australia. [PDF]

Astrobiology, 2013
Conner AJ, Benison KC.
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source