The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti +8 more
wiley +1 more source
Fluid inclusion stratigraphy (FIS) data for the following exploratory oil/gas wells: Exxon Corporation Canning River Unit Block A-1, Exxon Corporation Canning River Unit B-1, ARCO Alaska Inc. Kavik #1, and ARCO Alaska Inc. Kavik Unit #2 [PDF]
openalex +1 more source
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Microthermometry and chemical composition of fluid inclusions from the Mt Chalmers volcanic-hosted massive sulfide deposits, central Queensland, Australia: implications for ore genesis [PDF]
Khin Zaw +5 more
openalex +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Redox and magma recharge controls on excess sulfur build-up at Mount Samalas, 1257 CE. [PDF]
Ding S +6 more
europepmc +1 more source
Near‐infrared and Visible Light Microthermometry of Fluid Inclusions in Sphalerite from a Possible Southeast Extension of the Toyoha Polymetallic Deposit, Japan [PDF]
Toru Shimizu +2 more
openalex +1 more source

