Results 31 to 40 of about 184,719 (254)

Reported Hydration Beliefs and Behaviors without Effect on Plasma Sodium in Endurance Athletes

Frontiers in Physiology, 2017
Purpose: Little information is available on the association of hydration beliefs and behaviors in endurance athletes and exercise-associated hyponatremia (EAH).
Beat Knechtle, Beat Knechtle, Daniela Chlíbková, Pantelis T. Nikolaidis, Thomas Rosemann, Josef Bednář   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Analysis of Fluid Intake During Pregnancy

Makara Journal of Health Research
Background: Pregnancy is an important process that affects the body’s daily water requirements through various mechanisms. Adequate fluid intake also plays a critical role in pregnancy.
Irem Dilaver, Busra Parlak Somuncu, Murat Topbas, Kubra Sahin, Medine Gozde Ustundag, Cansu Agrali Gundogmus, Gamze Can, Nazim Ercument Beyhun   +7 more
doaj   +1 more source

EDUKASI DALAM MENINGKATKAN KEPATUHAN INTAKE CAIRAN PASIEN PENYAKIT GINJAL KRONIK (PGK) ON HEMODIALISIS

Critical Medical and Surgical Nursing Journal, 2019
Introduction: One of the causes of death in patients with chronic kidney disease on hemodialysis was due to the problem of uncontrolled fluid intake. The prevalence at Dr. Soetomo reported hospital as much as 80% increase weight more than 6%.
Desak Putu Kurniawati, Ika Yuni Widyawati, Herdina Mariyanti   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Impact of diet on renal stone formation

Journal of Family Medicine and Primary Care
Background and Objectives: The incidence of kidney stones is increasing globally, with a preponderance in adults compared with that in adolescents and children.
Solafa H Ghoneim, Hotoon Alghaythee, Bashair Alasmari, Osama Y Safdar   +3 more
doaj   +1 more source

My fluid diary sebagai alternatif pencatatan asupan cairan harian: studi crossover pada remaja putri

Jurnal Gizi Klinik Indonesia, 2022
My fluid diary as an alternative tool for daily recording fluid intake: cross over study among adolescent girls Background: Water plays a vital role in the human body.
Hiya Alfi Rahmah, Izka Sofiyya Wahyurin, Ajeng Dian Purnamasari, Farah Paramita   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source