Results 161 to 170 of about 2,282,903 (300)

Development to implementation to evaluation: step-by-step approach to embedding a clinical trial of a machine learning algorithm in the electronic health record. [PDF]

JAMIA Open
Morrison E, Overley J, Wurm K, Mock D, Bhavani SV.   +4 more
europepmc   +1 more source

Hederagenin Attenuates Morphine Addiction via GABAA1‐Mediated Modulation of Ca2+–CaMK–CREB Signaling in Ventral Tegmental Dopaminergic Neurons

Advanced Science, EarlyView.
Hederagenin is identified as a GABAA1‐targeting natural compound that suppresses morphine‐associated reward by restraining Ca2+–CaMK–cAMP–CREB signaling in ventral tegmental dopaminergic neurons. RVG29‐modified liposomal delivery further enhances brain accumulation and behavioral efficacy, providing a mechanistically defined strategy for natural ...
Hongyang Jiang, Ziting Zhou, Nannan Xue, Jiasi Deng, Yuanyuan Zhou, Xinying Lv, Yuxuan Wang, Yi Zhang, Haotian Pan, Geyan Xu, Yinkun Tao, Mengran Li, Xin Cui, Hongyue Ma, Qian Wang, Zhigang Lu   +15 more
wiley   +1 more source

Optimization of CNC milling parameters for YXR-7 tool steel using fuzzy MARCOS: A multi-response approach to improve machining productivity. [PDF]

PLoS One
Arunkumar ALN, Kumar S, Nampoothiri KN, Jha A, Jaiswal A.   +4 more
europepmc   +1 more source

Brain Network Dynamics of Local and Global Predictive Processing in Aging

Advanced Science, EarlyView.
Separation of concurrent whole‐brain networks in source‐reconstructed magnetoencephalography (MEG) data suggests that healthy aging reorganizes, rather than uniformly attenuates, neural responses elicited from hierarchical auditory violations. Enhanced early sensory deviance processing alongside reduced higher‐order cognitive responses suggests a large‐
Mathias Houe Andersen, Gemma Fernández‐Rubio, David R. Quiroga‐Martinez, Mattia Rosso, Mathias Klarlund, Kit Melissa Larsen, Hartwig Roman Siebner, Morten L. Kringelbach, Peter Vuust, Leonardo Bonetti   +9 more
wiley   +1 more source

A Hybrid Intuitionistic Logic: Semantics and Decidability

, 2006
An intuitionistic, hybrid modal logic suitable for reasoning about distribution of resources was introduced by Jia and Walker. The modalities of the logic allow validation of properties in a particular place, in some place and in all places.
Chadha, R., Macedonio, D., Sassone, V.
core  

The philosophy of logic [PDF]

, 2015
Read, Stephen
core   +2 more sources

miniPROTACs: Bridging PROTACs and molecular glues with a new degron alphabet. [PDF]

Acta Pharm Sin B
Wang J.
europepmc   +1 more source

Passive Color Imaging Through Macroscopic Strong Scattering Media

Advanced Science, EarlyView.
Light reflected from distant targets is severely attenuated and scattered by dense fog. A color‐channel‐simulated, independently exposed sCMOS array (CISA), combined with a passive colorful de‐scattering pipeline (PCDP), captures and reconstructs extremely weak target signals.
Renrui Wang, Xiaoyu Wang, Jianyu Wang, Zhiyu Yang, Xiangyang Ji   +4 more
wiley   +1 more source

Modal logic and Philosophy

, 2007
Modal logic is one of philosophy’s many children. As a mature adult it has moved out of the parental home and is nowadays straying far from its parent.
Krister, Segerberg, Lindström, Sten,
core  

Fluid Logic for Machine Tool Control?: British Experimental Work at the College of Aeronautics

Measurement + Control, 1969
doaj   +1 more source