Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler +4 more
wiley +1 more source
Inhaled nucleic acid therapeutics for respiratory diseases: delivery barriers, translational challenges, and emerging solutions. [PDF]
Yu L +9 more
europepmc +1 more source
XChrom is a deep learning framework that integrates genomic sequence and single‐cell context to predict chromatin accessibility. It generalizes to unseen cells and genomic regions, enabling cross‐sample and cross‐species analysis. Applied to COVID‐19 patient data, XChrom reveals key transcriptional regulatory mechanisms and disease‐associated ...
Yuanyuan Miao +5 more
wiley +1 more source
A Seat at the (Dinner) Table: Food and Eating Practices in the Ontario Basic Income Pilot. [PDF]
Halpenny C +3 more
europepmc +1 more source
Automated pneumatic tourniquet for hemorrhage control evaluated using an adaptive testing platform. [PDF]
Winter TG +4 more
europepmc +1 more source
Orthopedic Mechanophenotype: A Structured Narrative Review of Multiscale Biomechanics, Mechanotransduction, and Clinical Decision-Making. [PDF]
Lan Z, Mu Z, Li H.
europepmc +1 more source
Beyond the Implant: Towards a Predictive, Preventive, Personalized and Participatory Approach to Patient-Centered Implant Dentistry-A Narrative Review. [PDF]
Valentini P +3 more
europepmc +1 more source
Exosome-Mimetic Nanotheranostics for Spatiotemporally Adaptive Sepsis Therapy: A Chemical Orthogonality Design Framework. [PDF]
Zhao X +7 more
europepmc +1 more source
Embodying physical computing into soft robots. [PDF]
Wang J, Zhou Z, Kahak A, Li S.
europepmc +1 more source

