Results 91 to 100 of about 307,192 (301)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

A Multi-agent Evolution Algorithm used for Input Shaping of a Repetitive Non-linear Dynamic System

open access: yes, 2018
This software uses Matlab/Simulink environment to simulate and optimize the performance of a so-called Digital Displacement Unit (a fluid power technology).
Fluid Power and Mechatronic Systems   +3 more
core   +1 more source

The influence of electromagnetic field models on the damper winding loss and heat calculation results of tubular hydro‐generator

open access: yesElectronics Letters
This study investigates the effect of electromagnetic field models on tubular hydro‐generator damper winding losses and heat calculations using an on‐site 36‐MW such generator as an example.
Meng‐qi Xu   +3 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Basic fluid system trainer [PDF]

open access: yes, 1991
This invention, a trainer mounted and housed within a mobile console, is used to teach and reinforce fluid principles to students. The system trainer has two centrifugal pumps, each driven by a corresponding two-speed electric motor.
Hay, G. D.   +5 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

A strategy for tough and fatigue-resistant hydrogels via loose cross-linking and dense dehydration-induced entanglements

open access: yesNature Communications
Outstanding overall mechanical properties are essential for the successful utilization of hydrogels in advanced applications such as human-machine interfaces and soft robotics.
Danming Zhong   +6 more
doaj   +1 more source

Parametric analysis and performance prediction of an ultra-low temperature cascade refrigeration freezer based on an artificial neural network

open access: yesCase Studies in Thermal Engineering
A thermodynamic analysis is proposed to improve the designing and operating parameters in an ultra-low temperature cascade refrigeration system (CRS). The expressions for predicted parameters of the CRS are obtained based on an artificial neural network (
Wenlian Ye   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

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