Results 51 to 60 of about 4,099,536 (286)

Design and Experimental Study on Divergent Magnetic Fluid Seal with Large Clearance and Dual Magnetic Sources

Advances in Materials Science and Engineering, 2022
In order to solve the leakage problem of rotating machinery under the condition of large clearance, a new type of divergent magnetic fluid sealing device with secondary magnetic source was designed. The magnetic field distribution in the clearance of the
Xiaolong Yang, Yunyun Song, Peng Sun, You Li   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

An Open Test Case for High-Speed Low-Pressure Turbines: The SPLEEN C1 Cascade

International Journal of Turbomachinery, Propulsion and Power
Aviation accounts for a significant share of global CO2 emissions, necessitating efficient propulsion technologies to achieve net-zero emissions by 2050.
Gustavo Lopes, Loris Simonassi, Samuel Gendebien, Antonino Federico Maria Torre, Marios Patinios, Nicolas Zeller, Ludovic Pintat, Sergio Lavagnoli   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Molecular dynamics simulation of boric acid extraction by isobutanol/isooctanol liquid-liquid extraction

Chemical Engineering Journal Advances
Boric acid, a vital chemical in industries, agriculture, and high-tech fields, is primarily extracted from Salt Lake brines via liquid-liquid extraction. The efficiency differences between alcohols remain unclear.
Jisheng Li, Xu Zhao, Yuheng Fan, Changyu Sun, Yufeng Hu, Laiyong Zhang, Fayan Zhu, Jilong Han   +7 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

High fluid pressures and high fluid flow rates in the Megasplay Fault Zone, NanTroSEIZE Kumano Transect, SW Japan

Geochemistry, Geophysics, Geosystems, 2012
Annular pressure while drilling data shows high fluid overpressures at Site C0001 in part of the megasplay fault zone of the NanTroSEIZE transect across the subduction zone of SW Japan.
J. Casey Moore, Myles Barrett, Moe Kyaw Thu   +2 more
doaj   +1 more source

Hypothesis for the mechanics and seismic behaviour of low-angle normal faults: the example of the Altotiberina fault Northern Apennines

Annals of Geophysics, 2002
Widespread mapping of low-angle normal faults in areas of former continental extension continues to prompt debate as to whether such structures may be seismically active at very low dips (?
C. Collettini
doaj   +1 more source