We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
Janus Photonic Graphics by Stratified Assembly of Two Distinct Colloids
Double‐sided Janus photonic micropatterns with vivid structural colors are fabricated through a single‐step bottom‐up strategy. Density‐driven stratification and depletion‐mediated crystallization of PMMA and PS binary colloids lead to exclusive lattices on opposite surfaces under centrifugal force.
Young Geon Kim +4 more
wiley +1 more source
Variations in central venous oxygen saturation and central venous-to-arterial carbon dioxide tension difference to define fluid responsiveness: a prospective observational study. [PDF]
Zhou X +7 more
europepmc +1 more source
Advances in Sustainable and Wearable Textile Based Soft Robotics
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas +6 more
wiley +1 more source
Improved Prediction of Fluid Responsiveness in Ventilated Patients With Low Tidal Volume: The Role of Preload Variation. [PDF]
Gordillo Brenes A +5 more
europepmc +1 more source
A reconfigurable RRAM platform utilizing thermally pre‐formed filaments (TPFs) is developed to realize robust hardware security. By exploiting the thermodynamic stochasticity of TPFs, exceptionally reliable physically unclonable functions (PUFs) are achieved.
Seongbin Kwon +4 more
wiley +1 more source
Suprasternal ascending or descending aortic velocity peak variability assessment to predict fluid-responsiveness in healthy volunteers: the SADAVA-V pilot prospective study. [PDF]
Sanfilippo F +7 more
europepmc +1 more source
Review of Thermally Activated Twisted Coiled Polymer Actuators: A Materials Science Perspective
Thermally activated twisted and coiled polymer actuators (TCPAs) combine lightweight design, large deformation, and scalable fabrication for soft robotic and wearable applications. This review connects polymer structure, processing history, helix geometry, and thermomechanical characterization to actuator performance, highlighting current challenges in
Nadja Schenk +3 more
wiley +1 more source
The Utility of Echocardiography in Estimating Fluid Responsiveness. [PDF]
Asogwa N +4 more
europepmc +1 more source
Shaping Matter with Acoustic Waves: From Particles to Functional Structures
Acoustic‐directed assembly is reviewed as a materials‐oriented strategy for organizing particles, polymers, metals, and biological systems into functional structures. The review distinguishes reversible manipulation from permanent structure formation through medium fixation, particle fixation, and in situ material generation, highlighting routes toward
Avraham Kenigsberg +5 more
wiley +1 more source

