Results 41 to 50 of about 1,767,668 (275)

Optimal fluid management strategies in patients with heart failure: a systematic review and meta-analysis of randomized controlled trials

open access: yesFrontiers in Cardiovascular Medicine
BackgroundFluid restriction is frequently recommended in heart failure (HF) management to prevent volume overload and improve clinical outcomes. However, the evidence supporting this practice remains limited.
Umar G. Adamu   +2 more
doaj   +1 more source

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim   +11 more
wiley   +1 more source

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida   +11 more
wiley   +1 more source

Adherence to diet and fluid restriction of individuals on hemodialysis treatment and affecting factors in Turkey [PDF]

open access: yes, 2015
AimThis study was conducted to determine adherence to diet and fluid restriction in hemodialysis-treated individuals and the affecting factors in Turkey.
Kocaoz, Semra, Efe, Dilek
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Perceptions of fluid restriction self-care in heart failure

open access: yes, 2018
Objectives: Daily fluid restriction reduces fluid retention and therefore lessens the symptom burden of heart failure but the literature shows that adherence is sub-optimal.
Kim N Walker, Jed S Duff, Leanna S Woods
core   +2 more sources

Patient and caregiver perspectives of fluid discharge protocols following pituitary surgery

open access: yesJournal of Clinical & Translational Endocrinology
Background: Post-operative fluid restriction after transsphenoidal surgery (TSS) for pituitary tumors may effectively prevent delayed hyponatremia, the most common cause of readmission.
Julia J. Chang   +9 more
doaj   +1 more source

The effect of low central venous pressure on hepatic surgical field bleeding and serum lactate in patients undergoing partial hepatectomy: a prospective randomized controlled trial

open access: yesBMC Surgery, 2020
Background This prospective randomized controlled study was designed to evaluate the effect of fluid restriction alone versus fluid restriction + low central venous pressure (CVP) on hepatic surgical field bleeding, intraoperative blood loss, and the ...
Ling Yu   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Fourier restriction to polynomial curves I: a geometric inequality [PDF]

open access: yes, 2010
We prove a Fourier restriction result for general polynomial curves in Rd. Measuring the Fourier restriction with respect to the affine arclength measure of the curve, we obtain a universal estimate for the class of all polynomial curves of bounded ...
Wright, James   +5 more
core   +1 more source

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