Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching +9 more
wiley +1 more source
Fluid shear stress-mediated upregulated exosomal-IGF2 promotes hepatocellular carcinoma cell migration and metastasis. [PDF]
Feng T +9 more
europepmc +1 more source
Low‐Outgassing Liquid Metal–Silicone Composites for Multifunctional Space Applications
Integrating liquid metal microdroplets into a space‐grade silicone creates a multifunctional composite while preserving its inherent flexibility and low‐outgassing behavior. The composite has 11×$\times$ higher thermal conductivity while remaining thermally stable and maintaining a total mass loss of ≤$\le$ 1% under thermal vacuum testing.
Spencer Pak +5 more
wiley +1 more source
Numerical Simulation of Fluid Shear Stress Distribution in Microcracks of Trabecular Bone. [PDF]
Gao Y, Zhao S, Yang A.
europepmc +1 more source
Transparent, electrically conductive In–Zn–O thin films are solution‐processed by spin coating, inkjet printing, and, as demonstrated here for the first time, screen printing. The chosen deposition technique determines the solution composition, which in turn governs the resulting microstructure and optoelectronic performance.
Danjela Kuscer +3 more
wiley +1 more source
Correction: Pei et al. Fluid Shear Stress Regulates Osteogenic Differentiation via AnnexinA6-Mediated Autophagy in MC3T3-E1 Cells. <i>Int. J. Mol. Sci.</i> 2022, <i>23</i>, 15702. [PDF]
Pei T +8 more
europepmc +1 more source
Organoids as Building Blocks for Adaptive and Resilient Biohybrid Robots
ABSTRACT Biohybrid robots combine engineered living tissues with synthetic materials and have emerged as a promising class of soft robotic systems capable of mimicking biological functions such as biodegradability, energy efficiency and flexible motions. By integrating biological and synthetic components, these systems leverage complementary properties
Antonia Georgopoulou
wiley +1 more source
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy +13 more
wiley +1 more source
VE-PTP controls a fluid shear stress set point that governs cell morphological responses through Tie-2. [PDF]
Shirakura K +3 more
europepmc +1 more source
Permanent magnet putty (PMP) integrates high‐coercivity NdFeB particles with a dynamic polyborosiloxane–Ecoflex matrix, achieving rapid self‐healing (90% mechanical recovery in 10 s) and magnetic recovery within 20 min. With twice the sensitivity of commercial putties, PMP enables precise 5–30 N force detection and discrimination between pressing and ...
Ruotong Zhao +5 more
wiley +1 more source

