Results 41 to 50 of about 76,531 (257)

Ion Channels in Endothelial Responses to Fluid Shear Stress [PDF]

Physiology, 2016
Fluid shear stress is an important environmental cue that governs vascular physiology and pathology, but the molecular mechanisms that mediate endothelial responses to flow are only partially understood. Gating of ion channels by flow is one mechanism that may underlie many of the known responses.
Kristin A, Gerhold, Martin A, Schwartz
openaire   +2 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Experimental study on the influence of cohesive sediment flocculation on the rheological properties of fluid mud

Shuili Shuiyun Gongcheng Xuebao
Fluid mud, widely distributed in coastal zones, estuaries, and reservoirs, significantly impacts regional ecosystems, environmental stability, and maritime navigation.
LIU Jie, ZHOU Yangsan, ZHOU Peng, XIAO Yi   +3 more
doaj   +1 more source

P300 Modulates Endothelial Mechanotransduction of Fluid Shear Stress. [PDF]

Cell Mol Bioeng
P300 is a lysine acetyltransferase that plays a significant role in regulating transcription and the nuclear acetylome. While P300 has been shown to be required for the transcription of certain early flow responsive genes, relatively little is known about its role in the endothelial response to hemodynamic fluid stress.
Whitworth CP, Aw WY, Doherty EL, Handler C, Ambekar Y, Sawhney A, Scarcelli G, Polacheck WJ.   +7 more
europepmc   +3 more sources

Neutrophil mechanotransduction: A GEF to sense fluid shear stress [PDF]

Journal of Cell Biology, 2016
Forces deriving from blood flow shear modulate vascular adherence and transendothelial migration of leukocytes into inflamed tissues, but the mechanisms by which shear is sensed are unclear. In this issue, Fine et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603109) identify the guanosine nucleotide exchange factor GEF-H1 as critical for ...
openaire   +2 more sources

Isogeometric Analysis for Fluid Shear Stress in Cancer Cells [PDF]

Mathematical and Computational Applications, 2020
The microenvironment of the tumor is a key factor regulating tumor cell invasion and metastasis. The effects of physical factors in tumorigenesis is unclear. Shear stress, induced by liquid flow, plays a key role in proliferation, apoptosis, invasion, and metastasis of tumor cells.
openaire   +3 more sources

GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors

FEBS Open Bio, EarlyView.
GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille, Shiva Rezaei, Julia Uffenorde, Oliver Gimm, Mohammad Ali Hosseinpour Feizi, Luiz Lehmann Coutinho, Carlos Guerrero‐Bosagna   +6 more
wiley   +1 more source

Experimental study of the fluidity of nanostructured magnetic fluid in a strong magnetic field

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов
Based on magnetic fluids, new effective technical devices have been implemented, such as magnetic fluid bearings, seals, and dampers. The magnetic-viscous effect inherent to magnetic fluids can not only improve the properties of magnetic fluid units, but
A.N. Bolotov, O.O. Novikova
doaj   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Shear stress correlations in hard and soft sphere fluids [PDF]

Molecular Physics, 2002
The shear stress autocorrelation function has been studied recently by molecular dynamics simulation using the 1/q^n potential for very large n. The results are analyzed and interpreted here by comparing them to the shear stress response function for hard spheres.
openaire   +2 more sources