Results 91 to 100 of about 427 (261)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Optimization of fluidized bed agglomeration process for developing a blackberry powder mixture. [PDF]

Heliyon, 2023
Cortés Rodríguez M, Gil G JH, Ortega-Toro R.   +2 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Effect of inflow conditioning for dry powder inhalers. [PDF]

Int J Pharm, 2021
Singh G, Lowe A, Azeem A, Cheng S, Chan HK, Walenga R, Kourmatzis A.   +6 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Glassy dynamics in active epithelia emerge from an interplay of mechanochemical feedback and crowding

Nature Communications
Glassy dynamics in epithelial tissues remain a subject of debate, as theory predicts its emergence only at unrealistically low cellular activity, yet experimental studies have shown glassy dynamics at physiologically active conditions.
Sindhu Muthukrishnan, Phanindra Dewan, Tanishq Tejaswi, Michelle B. Sebastian, Tanya Chhabra, Soumyadeep Mondal, Soumitra Kolya, Sumantra Sarkar, Medhavi Vishwakarma   +8 more
doaj   +1 more source

Hydrogen fluidised-bed reduction of Australian hematite-goethite iron ores

Cleaner Engineering and Technology
Fluidised-bed reactors are emerging as promising technologies for hydrogen reduction of low-grade iron ores. This study reports the fluidised-bed reduction behaviour of 4 low-grade ores with hematite-goethite mineralogy (57–61 wt% Fe) sourced from the ...
Daniel J. Lane, Bavinesh Maisuria, Sarah Spencer, Ben Rumsey, Sameer Usmani, John Pye, Alireza Rahbari, Keith R. Vining, Patrick G. Hartley, Matthew Watson, Chris W. Bumby   +10 more
doaj   +1 more source

Fluidisation under pressure

, 1976
Dissertation submitted for obtain the degree of Doctor of Philosophy, at the University of Cambridge - Darwin College, under the supervision of Dr. D. Harrison
openaire   +2 more sources