Results 81 to 90 of about 788,684 (250)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Novel electrorheological fluids with polymer particles containing organic dopants
S.338-347In a novel approach, electrorheological (ER) fluids based on doped polyurethane (PUR) particles were prepared and described. The dopants were electrically polar and polarizable organic substances either as guest molecules or as modifying agents ...
Reichert, Yanina, Böse, Holger
core +1 more source
Transition from dripping to jetting in power-law fluids
This computational study employs a finite volume method with axisymmetric coordinates and volume-of-fluid interface tracking to investigate the regime transition mechanisms from discrete droplet generation to continuous jet breakup in power-law fluid ...
Li, Kai +4 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Unsteady flow of Carreau fluids around an impulsively moving cylinder
Unsteady flow of Carreau fluids around an impulsively moving circular cylinder is numerically investigated in this study. Both shear-thinning and shear-thickening fluids are used with the range of the power-index number 0.4 1 with higher Cu and lower Re)
Yun, Yeji +5 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Some hexanamide-mono and di-linoleniate esters were prepared by the reaction of linolenic acid and hexanamide (derived from the reaction of hexanoic acid and diethanolamine).
M.M. Dardir +4 more
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Earthquake swarms are most commonly composed of small‐magnitude earthquakes. However, a recent study by Yoshida, Uchida, et al. (2023, https://doi.org/10.1029/2023GL106023) analyzed a swarm beneath the Noto Peninsula in Japan that, after more than two ...
David R. Shelly
doaj +1 more source

