Results 61 to 70 of about 5,308 (216)
Treatment of steroid-induced elevated intraocular pressure with anecortave acetate: a randomized clinical trial. [PDF]
, 2012 PURPOSE: The present study is the first randomized clinical trial designed to evaluate the intraocular pressure (IOP)-lowering effect of anecortave acetate (AA) administered at 3 doses (3, 15, or 30 mg) as an anterior juxtascleral depot (AJD) in patients
Bergamini, Michael V. W. +9 more
core +2 more sources
Mass spectrometry in ocular drug research
Mass Spectrometry Reviews, Volume 45, Issue 1, Page 37-68, January/February 2026.Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
Drug Delivery Implants in the Treatment of Vitreous Inflammation
Mediators of Inflammation, 2013 The eye is a model organ for the local delivery of therapeutics. This proves beneficial when treating vitreous inflammation and other ophthalmic pathologies.
Jillian Wang +3 more
doaj +1 more source
Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology
Journal of Cosmetic Dermatology, Volume 25, Issue 1, January 2026.ABSTRACT Background Melasma is a chronic, relapsing hyperpigmentation disorder driven by complex interactions among genetic predisposition, hormonal fluctuations, UV exposure, oxidative stress, inflammation, and photoaging. Its psychosocial impact is substantial, especially among women with darker skin types, and treatment remains challenging due to ...
Ting Liao +4 more
wiley +1 more source
Clinical Ophthalmology, 2013 Paul S Tlucek,1 James C Folk,1 Warren M Sobol,2 Vinit B Mahajan1,3 1Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USA; 2Retina Physicians and Surgeons, Dayton, OH, USA; 3Omics Laboratory, University of Iowa, Iowa ...
Tlucek PS, Folk JC, Sobol WM, Mahajan VB
doaj
Anti-Inflammatory Effect of Dexamethasone Controlled Released From Anterior Suprachoroidal Polyurethane Implants on Endotoxin-Induced Uveitis in Rats. [PDF]
, 2016 Targeted drug delivery to the ocular tissues remains a challenge. Biodegradable intraocular implants allow prolonged controlled release of drugs directly into the eye. In this study, we evaluated an anterior suprachoroidal polyurethane implant containing
Ayres, E. +13 more
core +2 more sources
Pediatric Dermatology, Volume 43, Issue 1, Page 145-148, January/February 2026.ABSTRACT Keratitis–ichthyosis–deafness (KID) syndrome is a rare genetic condition typically presenting at birth with ichthyosiform erythroderma and bilateral hearing loss and later progressing to diffuse keratodermatous plaques with scaling. The condition is associated with mutations in the GJB2 gene, which lead to aberrant activation of connexin ...
Radhika Gupta +3 more
wiley +1 more source
Design of an Implantable Device for Ocular Drug Delivery [PDF]
, 2012 Ocular diseases, such as, glaucoma, age-related macular degeneration (AMD), diabetic retinopathy, and retinitis pigmentosa require drug management in order to prevent blindness and affecting million of adults in USA and worldwide.
Atkinson, Gary M. +3 more
core +3 more sources
The Use of Tranexamic Acid to Treat Melasma: A Systematic Review and Meta‐Analysis
Dermatologic Therapy, Volume 2026, Issue 1, 2026.Introduction Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits bleeding due to its effects on plasminogen conversion, approved by the FDA to treat menorrhagia and prevent bleeding in hemophilia patients undergoing dental extraction.
Nabila Scabine Pessotti +7 more
wiley +1 more source