Results 251 to 260 of about 412,249 (328)

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

The PDE5 inhibitor vardenafil enhances glutamatergic transmission through amyloid-beta and cellular prion protein. [PDF]

open access: yesNeurotherapeutics
Kafi MAA   +9 more
europepmc   +1 more source

StarD5 Regulates Cholesterol Homeostasis to Promote Colorectal Cancer Progression and the Cancer Stem Cell Phenotype. [PDF]

open access: yesMol Cancer Res
Sharon C   +6 more
europepmc   +1 more source

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