Results 91 to 100 of about 380,681 (304)

Impending anterior ischemic optic neuropathy with elements of retinal vein occlusion in a patient on interferon for polycythemia vera. [PDF]

, 2012
We describe the course and likely pathophysiology of impending anterior ischemic optic neuropathy (AION) and retinal vein occlusion in a 56-year-old man with polycythemia vera managed with interferon alpha for 2 years.
Hirsch, Louis K, Rue, Kelly S, Sadun, Alfredo A   +2 more
core   +1 more source

Erythrocyte deformability correlates with microvascular ischemia and disease severity in diabetic retinopathy

Journal of Diabetes Investigation, EarlyView.
Under physiological conditions, deformable erythrocytes pass smoothly through the capillary network, maintaining retinal capillary perfusion (A). In pathological conditions, reduced erythrocyte deformability causes irregular passage and stagnation within capillaries, resulting in localized blood flow stasis and microvascular congestion, leading to ...
Ye Eun Han, Joon Seo Lim, Yulim Kim, Inhye Kim, Jun Sung Moon, Junyeop Lee   +5 more
wiley   +1 more source

\u3cem\u3eIn vivo\u3c/em\u3e Imaging of Human Retinal Microvasculature Using Adaptive Optics Scanning Light Ophthalmoscope Fluorescein Angiography [PDF]

, 2013
The adaptive optics scanning light ophthalmoscope (AOSLO) allows visualization of microscopic structures of the human retina in vivo. In this work, we demonstrate its application in combination with oral and intravenous (IV) fluorescein angiography (FA ...
Carroll, Joseph, Chui, Toco Y.P., Dubow, Michael, Dubra, Alfredo, Pinhas, Alexander, Rosen, Richard B., Scoles, Drew, Shah, Nishit, Sulai, Yusufu N., Walsh, Joseph B., Weitz, Rishard   +10 more
core   +1 more source

Imaging Canine Post‐Trabecular Aqueous Outflow Pathways: Effect of Acute Intraocular Pressure Elevation in Normal Eyes

Veterinary Ophthalmology, EarlyView.
ABSTRACT Purpose To investigate the relationship between increased intraocular pressure (IOP) and the structure of the post‐trabecular aqueous outflow tract of dogs. Methods Ex vivo aqueous angiography (AA) and anterior segment optical coherence tomography (OCT) were performed concurrently in 19 normal canine eyes, following cannulation and ...
Odalys Torné, Jacob P. Nilles, Andrew L. Smith, Kevin C. Snyder, Kazuya Oikawa, Julie A. Kiland, Mary R. Telle, Mark Banghart, Gillian J. McLellan   +8 more
wiley   +1 more source

Peripheral retinal avascularity and capillary leakage in central serous chorioretinopathy

Journal of Current Ophthalmology, 2019
Purpose: To report a novel finding of peripheral retinal avascularity (PRA) and peripheral capillary leakage (PCL) on wide-field fluorescein angiography (WFA) in non-dependent quadrants, in eyes with bilateral chronic central serous chorioretinopathy ...
V.G. Madanagopalan, Karan Shah, C.K. Nagesha, Prabu Baskaran   +3 more
doaj   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

Aging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong, Xiaoyan Han, Siyi Qi, Duo Li, Jingyue Zhang, Linyu Zhang, Shujie Zhang, Qin Jiang, Biao Yan, Chen Zhao   +9 more
wiley   +1 more source

Assessment of Ischemic Index in Retinal Vascular Diseases Using Ultra-Wide-Field Fluorescein Angiography:Single Versus Summarized Image [PDF]

, 2016
Background and Objective: To compare a single image with a computer-generated summarized image from the ultra-wide-field fluorescein angiogram (UWFFA) sequence for evaluation of ischemic index (ISI).Materials and Methods: UWFFA sequences from patients ...
Apap, David, Franco-Cardenas, Valentina, Heilweil, Gad, Hubschman, Jean Pierre, Joseph, Anthony, Shah, Sanket U., Trucco, Emanuele, Zutis, Kris   +7 more
core   +2 more sources

Long‐term outcome of Coats' disease: Implications for the classification of foveal vascular pathologies

Acta Ophthalmologica, Volume 104, Issue 1, Page e104-e111, February 2026.
Abstract Purpose To investigate the long‐term outcome in patients with Coats' disease regarding initial stages. Methods Within a retrospective, clinical, single centre study, patients with diagnosed Coats' disease treated from 1992 to 2019 (minimum follow‐up of 12 months) were investigated. A total of, 75 out of 123 patients met the inclusion criteria.
Claudia Brockmann, Bert Müller, Shideh Schönfeld, Sibylle Winterhalter, Oliver Zeitz, Antonia M. Joussen   +5 more
wiley   +1 more source

Observation of angiographic dye leakage in ocular surface squamous neoplasia

American Journal of Ophthalmology Case Reports, 2020
Purpose: The clinical diagnosis of ocular surface squamous neoplasia is challenging, mostly requiring excisional biopsy. Human tumor angiogenesis is characterized by abnormal vessel architecture and transvascular hyperpermeability.
Christoph Palme, Astrid Wanner, Vito Romano, Gertrud Haas, Stephen Kaye, Bernhard Steger   +5 more
doaj   +1 more source

A nonhuman primate model of inherited retinal disease. [PDF]

, 2019
Inherited retinal degenerations are a common cause of untreatable blindness worldwide, with retinitis pigmentosa and cone dystrophy affecting approximately 1 in 3500 and 1 in 10,000 individuals, respectively.
Artemyev, Nikolai O, Boyd, Kimberly, Cameron, Ashley, Chen, Rui, Davis, Sarah, Garzel, Laura, Gopalakrishna, Kota N, Harris, R Alan, Huang, Yijun, Kim, Soohyun, Li, Yumei, Liang, Qingnan, Moshiri, Ala, Murphy, Christopher J, Pomerantz, Ori, Raveendran, Muthuswamy, Roberts, Jeffrey, Rogers, Jeffrey, Stout, J Timothy, Thomasy, Sara M, Wang, Jun, Yiu, Glenn   +21 more
core