Germanium‐Based Long‐Conjugation Xanthene Fluorophores for Bioimaging in Optimal NIR‐II Sub‐Window
An NIR‐II dye (EGe5) integrates germanium‐enhanced vibrational suppression and extended conjugation, achieving unprecedented brightness in the optimal NIR‐IIx sub‐window. This design enables high‐contrast visualization of intestinal vasculature and renal labeling, overcoming traditional signal limitations. The tailored spectral properties highlight its
Jin Li+9 more
wiley +1 more source
Longitudinal imaging of microvascular remodelling in proliferative diabetic retinopathy using adaptive optics scanning light ophthalmoscopy [PDF]
Purpose To characterise longitudinal changes in the retinal microvasculature of type 2 diabetes mellitus (T2DM) as exemplified in a patient with proliferative diabetic retinopathy (PDR) using an adaptive optics scanning light ophthalmoscope (AOSLO ...
Cheang, Eric+8 more
core +2 more sources
Nonperfused Peripheral Retinal Area in Eyes with Chronic Rhegmatogenous Retinal Detachment
We report two cases of chronic rhegmatogenous retinal detachment with a nonperfused peripheral retinal area. Case 1 was an 84-year-old woman who presented with a bullous retinal detachment of the inferior retina and a best-corrected visual acuity of 20 ...
Tomoaki Tatsumi+3 more
doaj +1 more source
Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine
Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang+7 more
wiley +1 more source
Ophthalmic findings in Behcet׳s disease: Cases without apparent ocular signs
Purpose: To evaluate the fluorescein angiography and infrared autofluorescence finding in patients with confirmed Behcet׳s disease (BD) but without clinical ocular signs.
Hormoz Chams+6 more
doaj +1 more source
Study workflow. Neuroretinal changes were observed in alloxan‐induced diabetic rabbits, while the retinal vasculature remained unaffected, indicating the successful establishment of a diabetic neuroretinal model. Abstract Background Diabetic retinal neuropathy (DRN) leads to significant visual impairment; however, no existing animal model fully ...
Xinlu Li+9 more
wiley +1 more source
Optical Coherence Tomography Angiography Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes. [PDF]
PurposeThe purpose of this study was to compare retinal nerve fiber layer (RNFL) thickness and optical coherence tomography angiography (OCT-A) retinal vasculature measurements in healthy, glaucoma suspect, and glaucoma patients.MethodsTwo hundred sixty ...
Belghith, Akram+11 more
core
Concordância entre tomografia de coerência óptica e angiofluoresceinografia no edema macular cistóide secundário a cirurgia de catarata [PDF]
PURPOSE: To evaluate the agreement between optical coherence tomography (OCT) and fundus fluorescein angiography (FFA) regarding the detection of cystoid macular edema (CME) following cataract surgery.
Bonomo, Pedro Paulo+7 more
core +2 more sources
Ultra-Wide-Field Fluorescein Angiography in Microscopic Polyangiitis
A 25-year-old Hispanic female presented with 5 months of dry eyes and 2 months of bilateral photophobia and decreased vision. On examination, she had bilateral anterior uveitis and mild disc edema of the left eye.
Philip P. Storey+4 more
doaj +1 more source
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen+7 more
wiley +1 more source