Results 51 to 60 of about 761,145 (226)

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Ureterovesical Anastomosis Complications in Kidney Transplantation: Definition, Risk Factor Analysis, and Prediction by Quantitative Fluorescence Angiography with Indocyanine Green [PDF]

, 2022
Ureteral stenosis and urinary leakage are relevant problems after kidney transplantation. A standardized definition of ureterovesical anastomosis complications after kidney transplantation has not yet been established.
Alexander Meyer, Reissfelder, Christoph, Christel Weiss, Werner Lang, Schwenke, Kay, Kunath, Frank, Kay Schwenke, Ulrich Rother, Krämer, Bernhard K., Gerken, Andreas L. H., Weiss, Christel, Rahbari, Nuh N., Kai Nowak, Bernhard K. Krämer, Katharina Heller, Pauline Glossner, Heller, Katharina, Nowak, Kai, Ioannis Karampinis, Rother, Ulrich, Lang, Werner, Christoph Reissfelder, Karampinis, Ioannis, Andreas L. H. Gerken, Frank Kunath, Kriegmair, Maximilian C., Maximilian C. Kriegmair, Meyer, Alexander, Nuh N. Rahbari, Glossner, Pauline   +29 more
core   +1 more source

FLOW800−guided microsurgical resection of a brainstem hemangioblastoma with AVM−like features: a case report and technical note

Frontiers in Oncology
BackgroundBrainstem hemangioblastomas (HBs) are rare, highly vascularized benign tumors that pose significant surgical challenges due to their deep location, proximity to critical neural structures, and arteriovenous malformation (AVM)-like ...
Ying Yang, Ying Yang, Chunfeng Pan, Chuan He, Zhaobin Chen, Zhaoyi Quan, Gang Cao   +6 more
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

3D reconstruction of cerebral blood flow and vessel morphology from x-ray rotational angiography [PDF]

, 2009
Three-dimensional (3D) information on blood flow and vessel morphology is important when assessing cerebrovascular disease and when monitoring interventions.
Wächter, I., Wächter, I
core  

Intraoperative Multimodal Bowel Perfusion Quantification Combining Hyperspectral Imaging and Indocyanine Green

Diagnostics
Background/Objectives: Intraoperative perfusion imaging can support determining the anastomosis site to avoid leakages after colorectal surgery. Indocyanine green–fluorescence angiography (ICG-FA) and hyperspectral imaging (HSI) have been used recently ...
Georg Thiele, Annekatrin Pfahl, Hannes Köhler, Matthias Mehdorn, Sigmar Stelzner, Ines Gockel, Andreas Melzer, Boris Jansen-Winkeln   +7 more
doaj   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Inpatient coronary angiography and revascularisation following non-ST-elevation acute coronary syndrome in patients with renal impairment: a cohort study using the Myocardial Ischaemia National Audit Project. [PDF]

, 2014
BACKGROUND: International guidelines support an early invasive management strategy (including early coronary angiography and revascularisation) for non-ST-elevation acute coronary syndrome (NSTE-ACS) in patients with renal impairment.
Clive Weston, Damian Fogarty, Sapna Shah (579169), Clive Weston (579172), Claire C Sharpe, Retha Steenkamp, Steenkamp, Retha, Claire C. Sharpe (579173), Weston, Clive, Junghans, Cornelia, Sharpe, Claire C, Catriona Shaw, Fogarty, Damian, Damian Fogarty (579171), Weston Clive, Dorothea Nitsch, Shah Sapna, Retha Steenkamp (288231), O’Donoghue Donal, O'Donoghue, Donal, Fogarty Damian, Nitsch Dorothea, Catriona Shaw (579167), Junghans Cornelia, Dorothea Nitsch (232367), Shaw, Catriona, O’Donoghue, Donal, Sharpe, Claire C., Cornelia Junghans (579168), Donal O’Donoghue (579170), Cornelia Junghans, Sharpe, Claire C.; id_orcid, Shah, Sapna, Sharpe Claire C., Sapna Shah, Steenkamp Retha, Nitsch, Dorothea, Shaw Catriona, Donal O'Donoghue   +38 more
core   +2 more sources