Results 121 to 130 of about 99,563 (273)

Pericyte‐Assisted Vascular Lumen Organization in a Novel Dynamic Human Blood‐Brain Barrier‐on‐Chip Model

Advanced Healthcare Materials, EarlyView.
Organ‐on‐Chip (OoC) technology enables the precise modeling of the blood‐brain barrier (BBB). This study presents a microfluidic device that mimics brain microvessels, integrating co‐culture with pericytes and astrocytes under pulsatile flow. Results show that perivascular cells modulate endothelial morphology, promoting lumen formation and barrier ...
Vita Guarino, Elisabetta Perrone, Elisa De Luca, Alberto Rainer, Maura Cesaria, Alessandra Zizzari, Monica Bianco, Giuseppe Gigli, Lorenzo Moroni, Valentina Arima   +9 more
wiley   +1 more source

Graded Hydroxyapatite Triply Periodic Minimal Surface Structures for Bone Tissue Engineering Applications

Advanced Healthcare Materials, EarlyView.
This study investigates the role of triply periodic minimal structures in load bearing bone tissue engineering applications. Research uses a combination of mechanical testing, material characterization, and in vitro tests to study the impact of TPMS lattice structures (gyroid, lidinoid and split‐P).
Tejas M. Koushik, Catherine M. Miller, Elsa Antunes   +2 more
wiley   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Perovskite Light‐Emitting Diodes with Quantum Wires and Nanorods

Advanced Materials, EarlyView.
This review focuses on low‐dimensional perovskite materials and discusses their applications in light‐emitting diodes (LEDs). Special attention is given to the introduction of perovskite quantum wires and nanorods, two unique types of one‐dimensional (1D) materials, and their interesting optoelectronic properties.
Qianpeng Zhang, Daquan Zhang, Zebing Liao, Yang Bryan Cao, Mallem Kumar, Swapnadeep Poddar, Junchao Han, Ying Hu, Hualiang Lv, Xiaoliang Mo, Abhishek Kumar Srivastava, Zhiyong Fan   +11 more
wiley   +1 more source

Fluorescence anisotropy microplate assay for analysis of steroid receptor-DNA interactions

BioTechniques, 2004
To analyze the interactions of steroid/nuclear hormone receptors with their DNA response elements, we used ultra low-volume microplates to develop a simple and rapid fluorescence anisotropy assay. The novel fluorescence anisotropy microplate assay (FAMA)
Stanley Y. Wang, Bonnie S. Ahn, Rebecca Harris, Steven K. Nordeen, David J. Shapiro   +4 more
doaj   +1 more source

Isotropic reconstruction of 3D fluorescence microscopy images using convolutional neural networks [PDF]

arXiv, 2017
Fluorescence microscopy images usually show severe anisotropy in axial versus lateral resolution. This hampers downstream processing, i.e. the automatic extraction of quantitative biological data. While deconvolution methods and other techniques to address this problem exist, they are either time consuming to apply or limited in their ability to remove
arxiv  

The Deepest Blue: Major Advances and Challenges in Deep Blue Emitting Quasi‐2D and Nanocrystalline Perovskite LEDs

Advanced Materials, EarlyView.
In this review, the recent development of deep‐blue (≤465 nm) perovskite light‐emitting diodes (PeLEDs) are summarized, using different perovskite nanomaterials, including nanocrystals (NCs), quantum dots (QDs), nanoplatelets (NPLs), quasi‐2D thin film, 3D bulk thin film, as well as lead‐free perovskite nanomaterials.
Pui Kei Ko, Jianchao Ge, Pengbo Ding, Dezhang Chen, Hoi Lam Tammy Tsang, Nitish Kumar, Jonathan E. Halpert   +6 more
wiley   +1 more source

Built-in Fluorescence Anisotropy: an in vivo Imaging Probe for bis-Retinoid Products in Retina [PDF]

arXiv, 2019
Non-degradable fluorophores that accumulate as Lipofuscin in retinal pigment epithelium (RPE) cells has been a major source of intrinsic biomarker for quantifying the progression of several diseases, including age-related macular degeneration, Stargardt disease and, more.
arxiv  

Strategies for Controlling Emission Anisotropy in Lead Halide Perovskite Emitters for LED Outcoupling Enhancement

Advanced Materials, EarlyView.
The rise of lead halide perovskite semiconductors has enabled high‐performance LEDs with internal quantum efficiencies approaching 100%. In order to further enhance the external quantum efficiencies limited by light outcoupling effects, in this account, the strategies for reducing energy dissipation through the substrate, waveguide, and evanescent ...
Tommaso Marcato, Sudhir Kumar, Chih‐Jen Shih   +2 more
wiley   +1 more source

True equilibrium measurement of transcription factor-DNA binding affinities using automated polarization microscopy

Nature Communications, 2018
Methods to measure selective transcription factor-DNA binding often lack sensitivity and are not performed in solution. Here the authors develop a method to perform fluorescence anisotropy measurements of transcription factor-DNA binding energies with ...
Christophe Jung, Peter Bandilla, Marc von Reutern, Max Schnepf, Susanne Rieder, Ulrich Unnerstall, Ulrike Gaul   +6 more
doaj   +1 more source