Results 1 to 10 of about 1,071,713 (341)

An open-source, high-resolution, automated fluorescence microscope [PDF]

open access: goldeLife
Fluorescence microscopy is a fundamental tool in the life sciences, but the availability of sophisticated equipment required to yield high-quality, quantitative data is a major bottleneck in data production in many laboratories worldwide.
Ando Christian Zehrer   +3 more
doaj   +4 more sources

Multimodal fluorescence microscope with fast adaptive polarimetry [PDF]

open access: yesHardwareX, 2023
Polarized light microscopy is a widely used technique to observe specimens that are optically anisotropic, or birefringent. It has a broad applicability in the study of minerals, soft materials such as polymers, complex fluids or liquid crystals, and ...
Berta Martínez-Prat   +3 more
doaj   +5 more sources

Possibilities of using a miniature fluorescence microscope [PDF]

open access: diamondE3S Web of Conferences, 2020
The article discusses an approach to fluorescence microscopy using single-photon miniature fluorescence microscopes. The use of miniscopes allows you to expand the possibilities of their usage and solve many problems related to the need of fixing ...
Erofeev Alexander   +4 more
doaj   +2 more sources

A miniature fluorescence microscope for multi-plane imaging [PDF]

open access: yesScientific Reports, 2022
Miniature fluorescence microscopes are becoming an increasingly established tool to investigate neural circuits in freely moving animals. In this work we present a lightweight one-photon microscope capable of imaging at different focal depths.
Giovanni Barbera   +5 more
doaj   +2 more sources

Fluorescence microscope light source based on integrated LED [PDF]

open access: yesLight: Science & Applications, 2023
An LED-integrated excitation cube (LEC) was designed to address the limitations of conventional fluorescence lamps. The LEC has a decentralized structure, high optical power density, and efficient illumination.
Jianchen Zi, Hai Bi
doaj   +2 more sources

A Smartphone-Based Low-Cost Inverted Laser Fluorescence Microscope for Disease Diagnosis [PDF]

open access: yesBiosensors, 2022
Fluorescence microscopy is an important tool for disease diagnosis, often requiring costly optical components, such as fluorescence filter cubes and high-power light sources.
Omar Ormachea   +3 more
doaj   +2 more sources

A cryogenic, coincident fluorescence, electron, and ion beam microscope [PDF]

open access: goldeLife, 2022
Cryogenic electron tomography (cryo-ET) combined with subtomogram averaging, allows in situ visualization and structure determination of macromolecular complexes at subnanometre resolution.
Daan B Boltje   +15 more
doaj   +2 more sources

Automated microscope-independent fluorescence-guided micropipette

open access: goldBiomedical Optics Express, 2021
Glass micropipette electrodes are commonly used to provide high resolution recordings of neurons. Although it is the gold standard for single cell recordings, it is highly dependent on the skill of the electrophysiologist. Here, we demonstrate a method of guiding micropipette electrodes to neurons by collecting fluorescence at the aperture, using an ...
Christopher Miranda   +6 more
openaire   +3 more sources

Low-cost fluorescence microscope with microfluidic device fabrication for optofluidic applications [PDF]

open access: yesHardwareX, 2023
Optofluidic devices have revolutionized the manipulation and transportation of fluid at smaller length scales ranging from micrometers to millimeters. We describe a dedicated optical setup for studying laser-induced cavitation inside a microchannel. In a
Nagaraj Nagalingam   +8 more
doaj   +2 more sources

Homologous Recombination under the Single-Molecule Fluorescence Microscope. [PDF]

open access: yesInt J Mol Sci, 2019
Homologous recombination (HR) is a complex biological process and is central to meiosis and for repair of DNA double-strand breaks. Although the HR process has been the subject of intensive study for more than three decades, the complex protein–protein ...
Gibbs DR, Dhakal S.
europepmc   +3 more sources

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