Results 121 to 130 of about 1,071,713 (341)
Open Plans of a Multi-Functional, Low Cost Fluorescence Microscope for Teaching and Research [PDF]
, 2014 Victoria Nguyen +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Fluorescence Microscopic Image Cell Segmentation
International Journal of Future Computer and Communication, 2012 Apoptosis is a process of Programmed Cell Death (PCD) that is a naturally occurring process in the body. The defective apoptosis process will causes extensive variety of diseases, such as cancer, ischemic damage, and etc. Hence, apoptosis is widely applied in disease analysis and disease treatments.
Yung-Kuan Chan +5 more
openaire +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Optical pickup unit-based fluorescence microscope with autofocus and deep learning capabilities
Biomedical AnalysisAn autofocus, cost-effective fluorescence microscope instrument is made using a commercially available Blu-ray disc optical pickup head (OPU). This ABFM consists of the optical path, system control and the operation program.
Yuankai Zhao +4 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Fluorescence Microscopical Study on Amelogenesis
Archivum histologicum japonicum, 1960 1. In this study, we have tried to investigate the formation of dental hard tissues, especially amelogenesis, by utilizing a fluorescence microscope. As a result of this study, the secondary fluorescence of the sections stained with acridin orange as fluorochrom shows various and well differentiated fluorescence colors, which proves most effective.2 ...
Syoichi SUGA +4 more
openaire +2 more sources
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
A statistical resolution measure of fluorescence microscopy with finite photons
Nature CommunicationsFirst discovered by Ernest Abbe in 1873, the resolution limit of a far-field microscope is considered determined by the numerical aperture and wavelength of light, approximately $$\frac{\lambda }{2{NA}}$$ λ 2 N A .
Yilun Li, Fang Huang
doaj +1 more source
Improved direct-count method by fluorescence microscope for low-biomass ice core
Antarctic Record, 2012 Ice cores recovered from ice sheets contain microorganisms that were transported to the surface of the ice sheet along with airborne dust. The abundance of microorganisms in ice cores, as measured by direct cell count under a fluorescence microscope, is ...
Jun Uetake +2 more
doaj +1 more source