Results 121 to 130 of about 1,065,070 (295)

Fluorescence Microscopical Study on Amelogenesis

open access: yesArchivum histologicum japonicum, 1960
1. In this study, we have tried to investigate the formation of dental hard tissues, especially amelogenesis, by utilizing a fluorescence microscope. As a result of this study, the secondary fluorescence of the sections stained with acridin orange as fluorochrom shows various and well differentiated fluorescence colors, which proves most effective.2 ...
Syoichi SUGA   +4 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A statistical resolution measure of fluorescence microscopy with finite photons

open access: yesNature Communications
First discovered by Ernest Abbe in 1873, the resolution limit of a far-field microscope is considered determined by the numerical aperture and wavelength of light, approximately $$\frac{\lambda }{2{NA}}$$ λ 2 N A .
Yilun Li, Fang Huang
doaj   +1 more source

Improved direct-count method by fluorescence microscope for low-biomass ice core

open access: yesAntarctic Record, 2012
Ice cores recovered from ice sheets contain microorganisms that were transported to the surface of the ice sheet along with airborne dust. The abundance of microorganisms in ice cores, as measured by direct cell count under a fluorescence microscope, is ...
Jun Uetake   +2 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Easy and accessible way to calibrate a fluorescence microscope and to create a microplastic identification key. [PDF]

open access: yesMethodsX, 2023
Kukkola A   +7 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

A Forensic Approach in the Determination of Sequence of Strokes using Fluorescence Spectrometry

open access: yesJournal of Forensic Science and Medicine
Background: Fluorescence Microscope is a promising analytical method for the examination of the sequence of strokes of writing inks of different colours, brands, and models in a questioned document. Aims and Objectives: In the present article, an attempt
Vartika Khare, Anu Singla, Pawan Gupta
doaj   +1 more source

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