Results 131 to 140 of about 2,265,085 (386)

MicroAnalyzer: A Python Tool for Automated Bacterial Analysis with Fluorescence Microscopy [PDF]

arXiv, 2020
Fluorescence microscopy is a widely used method among cell biologists for studying the localization and co-localization of fluorescent protein. For microbial cell biologists, these studies often include tedious and time-consuming manual segmentation of bacteria and of the fluorescence clusters or working with multiple programs.
arxiv  

A cost-effective fluorescence mini-microscope for biomedical applications.

Lab on a Chip, 2015
We have designed and fabricated a miniature microscope from off-the-shelf components and a webcam, with built-in fluorescence capability for biomedical applications.
Y. S. Zhang, João Ribas, A. Nadhman, Julio Aleman, Šeila Selimović, S. Lesher‐Pérez, Ting Wang, V. Manoharan, S. Shin, Alessia Damilano, N. Annabi, M. Dokmeci, S. Takayama, A. Khademhosseini   +13 more
semanticscholar   +1 more source

Fluorescence Microscopic Observations on the Dog Retina

Archivum histologicum japonicum, 1968
The dog retina was investigated with the fluorescence microscopical method for catecholamines introduced by FALCK and his co-workers (1962).Dopamine was administered intravenously, intraventricularly and intravitreously. Both intravenous and intraventricular dopamine significantly increased the number of the fluorescent amacrine cells.
Hitoshi Yoshikawa, Masao Konishi, Yutaka Sano   +2 more
openaire   +4 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Performance of light-emitting diode fluorescence microscope for diagnosis of tuberculosis

International Journal of Mycobacteriology, 2013
Background: Fluorescence microscopy (FM) over the years has shown the potential for increasing the performance of microscopy. The present study was aimed to access the performance of the LED microscope for the detection of acid fast bacilli in a ...
Manpreet Bhalla, Zeeshan Sidiq, P P Sharma, Ritu Singhal, V P Myneedu, Rohit Sarin   +5 more
doaj   +1 more source

Electroluminescence from a polythiophene molecular wire suspended in a plasmonic scanning tunneling microscope junction [PDF]

, 2014
The electroluminescence of a polythiophene wire suspended between two metallic electrodes is probed using a scanning tunneling microscope. Under positive sample voltage, the spectral and voltage dependencies of the emitted light are consistent with the ...
Dappe, Yannick J., Mathevet, Fabrice, Reecht, Gaël, Scheurer, Fabrice, Schull, Guillaume, Speisser, Virginie   +5 more
core   +3 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Enhancement of Fluorescent Labeling via a Composited Thin Film

International Journal of Polymer Science, 2014
Fluorescent labeling is the prevailing imaging technique in cell biological research. When statistical investigations on a large number of cells are involved, experimental study is required for both low magnification to get a reliable statistical ...
Taikei Suyama, Xiaowei Ji, Yaoju Zhang
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Instant three-color multiplane fluorescence microscopy

Biophysical Reports, 2021
One of the most widely used microscopy techniques in biology and medicine is fluorescence microscopy, offering high specificity in labeling as well as maximal sensitivity. For live-cell imaging, the ideal fluorescence microscope should offer high spatial
Ingo Gregor, Eugenia Butkevich, Jörg Enderlein, Soheil Mojiri   +3 more
doaj