Results 161 to 170 of about 2,265,085 (386)

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

FEBS Open Bio, EarlyView.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel, Maurice Tust, Samira Boussettaoui, Dietmar Fischer, Dirk Gründemann   +4 more
wiley   +1 more source

Bio-Sulfur Pre-Treatment Suppresses Anthracnose on Cucumber Leaves Inoculated with Colletotrichum orbiculare

Mycobiology, 2019
Bio-sulfur can be produced in the process of desulfurization from a landfill and collected by some microorganism such as Thiobacillus sp. as a sulfur element.
Eun Ju Ko, Yong Ho Shin, He Nam Hyun, Hyo Soon Song, Jeum Kyu Hong, Yong Chull Jeun   +5 more
doaj   +1 more source

Direct Observation of Specific Messenger RNA in a Single Living Cell under a Fluorescence Microscope [PDF]

, 2000
Akihiko Tsuji, Hiroyuki Koshimoto, Yoshihiro Sato, Masahiko Hirano, Yukari Sei-Iida, Satoshi Kondo, Kaname Ishibashi   +6 more
openalex   +1 more source

Establishment and biological characterization of radioresistant colorectal cancer cell lines

FEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu, Qing Dai, Jing Leng, Lin Fang, Jing‐Jing Ma, Rui Chen, Che Chen, Peng‐Fei Ran, Wen‐Wen Zhou, Chang Liu, Huang‐Fei Yu   +10 more
wiley   +1 more source

Epi-illumination SPIM for volumetric imaging with high spatial-temporal resolution. [PDF]

, 2019
We designed an epi-illumination SPIM system that uses a single objective and has a sample interface identical to that of an inverted fluorescence microscope with no additional reflection elements.
Chen, Xingye, Cheng, Karen W, Cho, Nathan H, Feng, Siyu, Huang, Bo, Leonetti, Manuel D, Lord, Samuel J, Mullins, R Dyche, Pessino, Veronica, Stuurman, Nico, Wang, Yina, Xie, Dan, Xu, Linfeng, Xu, Linfeng, Yang, Bin   +14 more
core   +1 more source

Novel Use of Fluorescence Illumination with an Infrared Microscope [PDF]

, 2000
Thomas J. Tague, Lisa M. Miller
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Three filters for the enhancement of the images acquired from fluorescence microscope and weak-light-sources and the image compression. [PDF]

Heliyon, 2023
Jia M, Xu J, Yang R, Li Z, Zhang L, Wu Y.   +5 more
europepmc   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

A statistical resolution measure of fluorescence microscopy with finite photons

Nature Communications
First discovered by Ernest Abbe in 1873, the resolution limit of a far-field microscope is considered determined by the numerical aperture and wavelength of light, approximately $$\frac{\lambda }{2{NA}}$$ λ 2 N A .
Yilun Li, Fang Huang
doaj   +1 more source