Results 181 to 190 of about 1,071,713 (341)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

From Fast Fluorescence Imaging to Molecular Diffusion Law on Live Cell Membranes in a Commercial Microscope

, 2014
Carmine Di Rienzo, Enrico Gratton, Fabio Beltram, Francesco Cardarelli   +3 more
openalex   +2 more sources

Design of a Long-Pass Filter with Effects on Fluorescence Image Observation for Surgical Fluorescence Microscope Applications [PDF]

, 2021
Jinkyu Kim, Ki‐Cheol Yoon, Kwang Gi Kim   +2 more
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Fluorescence intensity and bright spot analyses using a confocal microscope for photodynamic diagnosis of brain tumors

, 2016
T. Yoneyama, Tetsuyou Watanabe, Hiroyuki Kagawa, Yutaka Hayashi, Mitsutoshi Nakada   +4 more
openalex   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Application of Fluorescence In Situ Hybridization Assisted by Fluorescence Microscope in Detection of Her2 Gene in Breast Cancer Patients.

Contrast Media Mol Imaging, 2022
Lu F, Zhou T, Liu Y, Song L, Zhang B, Li Y.   +5 more
europepmc   +1 more source

Improvement of Detection Limits for Particle Contamination by Confocal Configuration in X-Ray Fluorescence Microscope

, 2021
H. Nakano, Shintaro Komatani, T. Matsuyama, Kouichi Tsuji   +3 more
openalex   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

SIL-based confocal fluorescence microscope for investigating individual nanostructures

Open Physics, 2011
Krajnik Bartosz, Schulte Tim, Piątkowski Dawid, Czechowski Nikodem, Hofmann Eckhard, Mackowski Sebastian   +5 more
doaj   +1 more source