Results 41 to 50 of about 10,837 (254)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Seasonal dynamics of dissolved organic matter in a small tropical estuary-coastal bay continuum: distribution, transformation, flux, and global perspectives

Frontiers in Marine Science
The export and transformation of riverine dissolved organic matter (DOM) at the river-sea interface are critical to understanding carbon budgets in tropical regions, yet remain underexplored in small watersheds.
Pengfei Liu, Kuan Jiang, Qi Tan, Fajin Chen, Renming Jia, Chao Wang, Chao Wang, Chao Wang, Chao Wang   +8 more
doaj   +1 more source

Linkages among fluorescent dissolved organic matter, dissolved amino acids and lignin-derived phenols in a river-influenced ocean margin

Frontiers in Marine Science, 2015
Excitation emission matrix (EEM) fluorescence spectroscopy coupled with parallel factor analysis (PARAFAC) is commonly used to investigate the dynamics of dissolved organic matter (DOM). However, a lack of direct comparisons with known biomolecules makes
Youhei eYamashita, Cédric G. Fichot, Yuan eShen, Rudolf eJaffé, Ronald eBenner, Ronald eBenner   +5 more
doaj   +1 more source

Photodegradation of fluorescent dissolved organic matter in river waters

GEOCHEMICAL JOURNAL, 2007
Photodegradation of dissolved organic matter (DOM), collected from two upstream and one downstream sites in the Lake Biwa watershed in Japan, was investigated using fluorescence properties of three-dimensional excitation emission matrix (3-D EEM).
MOSTOFA, KHAN M. G., YOSHIOKA, TAKAHITO, KONOHIRA, EIICHI, TANOUE, EIICHIRO   +3 more
openaire   +2 more sources

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

In-Situ Variability of DOM in Relation with Biogeochemical and Physical Parameters in December 2017 in Laucala Bay (Fiji Islands) after a Strong Rain Event

Journal of Marine Science and Engineering, 2021
Heavy rain events alter the biogeochemical outflows, affects water quality and ecosystem health within the coastal waters of small Pacific Islands. We characterized snapshots of the optical fingerprints of dissolved organic matter (DOM) sources together ...
Timoci Koliyavu, Chloe Martias, Awnesh Singh, Stéphane Mounier, Philippe Gérard, Cecile Dupouy   +5 more
doaj   +1 more source

Properties of fluorescent dissolved organic matter in the Gironde Estuary

Organic Geochemistry, 2009
The isolation, characterization and study of the properties of aquatic dissolved organic matter (DOM) still represent a challenge because of the heterogeneity, complexity and low concentration of organic material in natural waters. Based on its ability to interact with contaminants and thus to modify their transport and bioavailability, DOM is of ...
Huguet, Arnaud, Vacher, Lilian, Relexans, Stéphane, Saubusse, Sylvain, Froidefond, Jean-Marie, Parlanti, Edith   +5 more
openaire   +1 more source

3D Printing Innovations in Polymeric Porous and Patterned Architecture

Advanced Functional Materials, EarlyView.
Polymeric foams occupy a unique structural space between dense solids and open networks, where engineered void fraction governs mechanical compliance, thermal resistance, and mass transport. Additive manufacturing now enables precise spatial control over cellular architecture, unlocking designer foam structures across applications spanning crash ...
Dhanush Patil, Sri Vaishnavi Thummalapalli, Clarissa Westover, Arunachalam Ramanathan, M. Taylor Sobzcak, Roumika Patil, Qixuan Xiang, Tiantian Li, Sui Yang, Timothy E. Long, Hongyue Sun, Xianqiao Wang, Yang Liu, Kenan Song   +13 more
wiley   +1 more source

Remote sensing monitoring of fluorescent dissolved organic matter in Admiralty Bay: fusion of multi-source signal removal and machine learning

Science of Remote Sensing
Fluorescent dissolved organic matter (fDOM), a fluorescent component of dissolved organic matter (DOM), plays a crucial role in tracing pollution pathways in marine environments.
Ruiwu Zhang, Ruru Deng, Jun Ying, Jiayi Li, Yu Guo, Junying Yang, Cong Lei   +6 more
doaj   +1 more source