Results 131 to 140 of about 2,459,362 (303)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Advancing neutron imaging techniques to highest resolution with fluorescent nuclear track detectors
Scientific ReportsNeutron imaging is a nondestructive and noninvasive inspection technique with a wide range of potential applications. However, the fundamentals of this technique still need to be improved, one of which involves achieving micrometer scale or even better ...
Abdul Muneem +11 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
HLMiller-Imaging/SlowMembraneDiffusionAnalysis: Version 1
<h2>What's Changed</h2> <ul> <li>Addcode by @HLMiller-Imaging in https://github.com/HLMiller-Imaging/SlowMembraneDiffusionAnalysis/pull/1</li> <li>TrajectoryBugFix by @HLMiller-Imaging in https://github.com/HLMiller ...
HLMiller-Imaging
core +1 more source
Bimodal paramagnetic and fluorescent liposomes for cellular and tumor magnetic resonance imaging
, 2008 A novel bimodal fluorescent and paramagnetic liposome is described for cellular labeling. In this study, we show the synthesis of a novel gadolinium lipid, Gd.DOTA.DSA, designed for liposomal cell labeling and tumor imaging.
Oliver, M.H. +8 more
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Spectral Separation of Quantum Dots within Tissue Equivalent Phantom Using Linear Unmixing Methods in Multispectral Fluorescence Reflectance Imaging [PDF]
Introduction Non-invasive Fluorescent Reflectance Imaging (FRI) is used for accessing physiological and molecular processes in biological media. The aim of this article is to separate the overlapping emission spectra of quantum dots within tissue ...
نجف زاده, ابراهیم +3 more
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Applications Of Microspectroscopy, Hyperspectral Chemical Imaging And Fluorescence Microscopy In Chemistry, Biochemistry, Biotechnology, Molecular And Cell Biology [PDF]
, 2011 Chemical imaging is a technique for the simultaneous measurement of spectra (chemical information) and images or pictures (spatial information)^1,2^. The technique is most often applied to either solid or gel samples, and has applications in chemistry ...
I. C. Baianu
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Carbonic Anhydrase IX Targeted Polyaspartamide fluorescent Probes for Tumor imaging [PDF]
Yu Zhang,1,2 Fan Liu,2,3,* Chuntao Shao,2,* Jun Huang,3 Guoping Yan1 1College of Chemical and Material Engineering, Quzhou University, Quzhou, Zhejiang Province, 324000, People’s Republic of China; 2School of Materials Science and Engineering ...
Huang J, Zhang Y, Liu F, Yan G, Shao C
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