Developing a Novel Fluorescent Probe for Selectively Recognizing NQO1 in Cancer Cells and at the Tail Amputation Site of Zebrafish. [PDF]
Sun S, Ji Y, Chen G, Wang R, Pu S.
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
A pyrene-based fluorescent probe for highly sensitive and selective detection of hydroxylamine in environmental water samples. [PDF]
Zhang WJ +7 more
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Synthesis and characterization of a glutathione-responsive NIR-II fluorescent probe with Fenton-like reaction activity. [PDF]
Wu H +6 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Rational design of a fluorescent probe for the enantioselective and chemoselective recognition of chiral cysteine in wheat. [PDF]
Yu X +8 more
europepmc +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Room-Temperature Aqueous Synthesis of Amino-Functionalized Al-Based MOF as a Ratiometric Fluorescent Probe for Aqueous Dichromate Detection. [PDF]
Huang C +8 more
europepmc +1 more source

