Results 191 to 200 of about 340,246 (317)

Real-Time Detection of Burn Wound Infection via a Turn-On NIR-II Fluorescent Probe. [PDF]

Chemistry
Lu K, Yang S, Wang M, Zhang M, Zhou B, Yang K, Kirienko NV, Xiao H.   +7 more
europepmc   +1 more source

Fluorescence probes

Presentation of novel optical probes for fluorescence sensing in ...
openaire   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A fluorescent probe under the microscope showing dual recognition of B-DNA and G-quadruplex DNA. [PDF]

Commun Chem
Gramolini L, López-Corbalán R, Marazzi M, García-Iriepa C.   +3 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

A Dual Quantum Dot Fluorescent Probe for Time-Resolved Chemometric Detection of Chloramphenicolin Pharmaceuticals. [PDF]

Nanomaterials (Basel)
Castro RC, Páscoa RNMJ, Santos JLM, Ribeiro DSM.   +3 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Multicenter ex vivo evaluation of an α-mannosidase-targeted fluorescent probe for intraoperative margin assessment in breast cancer. [PDF]

Sci Rep
Ueo H, Ueo H, Doi T, Yamaguchi M, Akashi-Tanaka S, Takamaru T, Tsuda H, Moriya T, Yamaguchi R, Kozuka Y, Sasaki T, Gamachi A, Kai Y, Kubota Y, Kunii S, Nagamori Y, Fujita K, Urano Y, Ando Y, Mimori K, Masuda T.   +20 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Retraction of 'Real-time monitoring of DNA G-quadruplexes in living cells with a small-molecule fluorescent probe'. [PDF]

Nucleic Acids Res
europepmc   +1 more source