Results 191 to 200 of about 373,477 (302)

Correction: Regioselective synthesis of aza-saccharins <i>via</i> anionic [1,4] Fries-type rearrangement of aryl sulfonimidoyl fluorides. [PDF]

Chem Sci
Leypold M, Poli L, Earl M, Putra OD, Kwapien K, Lewis RJ, Murphy JJ, Passamonti M, von Sydow LM, Spelling V, Asproudis I, Sardana M, Gatti C, Seki H, Lemaitre T, Juskaite R, Gopalakrishnan R, Francis SJ, Gardelli C, Norrby PO, Czechtizky W.   +20 more
europepmc   +1 more source

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

Advanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen, Qimeng Wang, Ke Yang, Qinghai Lian, Xuyun Peng, Zhiyong Gong, Xinyi Zhao, Yong Wu, Tian Tao, Siqi Xu, Yifan Chen, Xiaoyan Tang, Jinghui Guo, Geyang Xu, Qi Zhang   +14 more
wiley   +1 more source

AgBF₄-catalyzed insertion of unactivated alkynes into C-F bonds of acyl fluorides. [PDF]

Chem Sci
Emmei T, Tobisu M.
europepmc   +1 more source

Fluoride intake from food and beverages by 1to-3-year-old toddlers attending a preventive dental program

Purpose: To evaluate fluoride (F) intake by 1–3-year-old children from the diet, as well as F concentrations in fingernails and toenails. Methods: Twelve-month-old Children (n=202), participants in a Preventive Dental Program for infants, had their F ...
Dezan, Cássia Cilene, Delbem, Alberto Carlos Botazzo [UNESP], Hosida, Thayse Yumi [UNESP], Salama, Isabel Cristina Cabral de Assis [UNESP], Ferraresso, Lucas Fernando Oliveira Tomáz [UNESP], Mancilla, Jorge Orlando Francisco Cuéllar, Pessan, Juliano Pelim [UNESP], Nagata, Mariana Emi, Sampaio, Caio [UNESP]   +8 more
core  

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Caries prevention in permanent teeth - basic recommendations of the German S 3 guideline. [PDF]

Clin Oral Investig
Nadine S, Elmar H, Werner G, Stefan R.
europepmc   +1 more source

Disorder‐Induced Extremely Low Thermal Conductivity of Graphite Fluoride

Advanced Science, EarlyView.
This article investigates the effect of fluorination on the thermal conductivity of graphite fluoride, demonstrating the relationship between structural modification and thermal conductivity in an extreme case. The record‐low through‐plane thermal conductivity measured in exfoliated graphite fluoride flakes was found to correlate with the wide ...
Wonsik Lee, Donghoon Moon, Ziyan Qian, Jinwoo Kim, Changheon Kim, Yeojin Lee, Hyobin Yoo, Richard B. Wilson, Qiye Zheng, Gwan‐Hyoung Lee, Hyejin Jang   +10 more
wiley   +1 more source

Polyphosphate-based strategies in enamel remineralization: mechanisms, evidence, and clinical potential. [PDF]

Front Oral Health
Seffahi B, El Ouarti I, Abdallaoui F.
europepmc   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Targeting Bifidobacterium animalis alleviates high-fluoride exposure-induced kidney injury in mice. [PDF]

AMB Express
Chen Y, Sun N, Gan B, He Y, Luo J, Pan K, Zeng Y, Jing B, Zeng D, Ni X.   +9 more
europepmc   +1 more source