Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Fluoride prophylaxis - poison or simple way to get rid of early childhood caries (ECC) – review
Introduction: As a prevention, fluoride is used systemically as well as topically in the oral cavity. Thanks to fluoride prophylaxis, one of the most common bacterial disease in the world can be significantly reduced. This disease is dental caries.
Justyna Molczyk-Sieńczak +9 more
doaj +1 more source
Synthesis, x-ray structure and anion binding properties of a cryptand-like hybrid calixpyrrole [PDF]
The novel cryptand in/out-3, containing two tripyrrolemethane units briged by three 1,3- diisopropylidenbenzene arms was readily synthesized by a convergent three-step synthesis. It binds fluoride by inclusion with excellent selectivity with respect to a
Cafeo, Grazia +6 more
core +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Local structural analyses on molten terbium fluoride in lithium fluoride and lithium–calcium fluoride mixtures [PDF]
X-ray absorption fine structure (XAFS) measurements on terbium fluoride in molten lithium fluoride and in molten lithium–calcium fluoride mixtures, (e.g.
Akatsuka, Hiroshi +12 more
core +2 more sources
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Laser irradiation prevents root caries: Microhardness and scanning electron microscopy analysis
Context: A promising option for the prevention of dental caries is the use of laser irradiation. Aims: Evaluate the effects of Er:YAG, Nd:YAG, and CO2 laser irradiation, associated or not to 2% sodium fluoride (2% NaF), on root caries prevention ...
Cesar P Lepri +4 more
doaj +1 more source
Effect of fluoride on the calcification of allogenic bone implants in rats [PDF]
Thesis (M.Sc.D.)--Boston University School of Graduate Dentistry, 1974. Periodontics.Bibliography included.In twenty-five (25) male adult rats which had decalcified allogenic bone implants placed in mid-fibular gaps and kept on a low-fluoride casein ...
Brown, Marvin L., Burdine, John T.
core
Red Mn4+-doped fluoride phosphors : why purity matters [PDF]
Traditional light sources, e.g., incandescent and fluorescent lamps, are currently being replaced by white light-emitting diodes (wLEDs) because of their improved efficiency, prolonged lifetime, and environmental friendliness.
Detavernier, Christophe +6 more
core +2 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source

