Results 131 to 140 of about 3,231,427 (376)

A Fluoride-Derived Electrophilic Late-Stage Fluorination Reagent for PET Imaging [PDF]

open access: yes, 2011
The unnatural isotope fluorine-18 \((^{18}F)\) is used as a positron emitter in molecular imaging. Currently, many potentially useful \(^{18}F\)-labeled probe molecules are inaccessible for imaging because no fluorination chemistry is available to make ...
Boursalian, Gregory Bagrad   +8 more
core   +1 more source

Covalent Binding of Dexamethasone to Polyimide Improves Biocompatibility of Neural Implantable Devices

open access: yesAdvanced Healthcare Materials, EarlyView.
The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin   +19 more
wiley   +1 more source

Generic semi-automated radiofluorination strategy for single domain antibodies: [18F]FB-labelled single domain antibodies for PET imaging of fibroblast activation protein-α or folate receptor-α overexpression in cancer

open access: yesEJNMMI Radiopharmacy and Chemistry
Background Radiofluorination of single domain antibodies (sdAbs) via N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) has shown to be a promising strategy in the development of sdAb-based PET tracers. While automation of the prosthetic group (PG) [18F]SFB
Herlinde Dierick   +11 more
doaj   +1 more source

Study of the Tissue Distribution of TLQP-21 in Mice Using [18F]JMV5763, a Radiolabeled Analog Prepared via [18F]Aluminum Fluoride Chelation Chemistry

open access: yesFrontiers in Pharmacology, 2018
TLQP-21 is a neuropeptide that is involved in the control of several physiological functions, including energy homeostasis. Since TLQP-21 could oppose the early phase of diet-induced obesity, it has raised a huge interest, but very little is known about ...
Elia A. Turolla   +24 more
doaj   +1 more source

Futureproofing [18F]Fludeoxyglucose manufacture at an Academic Medical Center [PDF]

open access: yes, 2018
Background We recently upgraded our [18F]fludeoxyglucose (FDG) production capabilities with the goal of futureproofing our FDG clinical supply, expanding the number of batches of FDG we can manufacture each day, and improving patient ...
Alicea, Jeremiah   +13 more
core   +1 more source

Concurrent Biocompatibility and Antimicrobial Functionality of Soft Diamond‐Like Carbon Coating for Healthcare Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
Designing an engineering material that simultaneously promotes the growth of beneficial biological cells while eliminating harmful bacteria is often challenging. However, this study presents a unique carbon coating by manufacturing design capable of achieving both functions, demonstrating strong potential for various applications, including medical ...
Abdul Wasy Zia   +8 more
wiley   +1 more source

Phase-III Clinical Trial of Fluorine-18 Flurpiridaz Positron Emission Tomography for Evaluation of Coronary Artery Disease.

open access: yesJournal of the American College of Cardiology, 2020
J. Maddahi   +8 more
semanticscholar   +1 more source

The Role of Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography in Aggressive Histological Subtypes of Thyroid Cancer: An Overview

open access: yesInternational Journal of Endocrinology, 2013
Aggressive histological subtypes of thyroid cancer are rare and have a poor prognosis. The most important aggressive subtypes of thyroid cancer are Hürthle cell carcinoma (HCTC) and anaplastic and poorly differentiated carcinoma (ATC and PDTC).
G. Treglia   +5 more
semanticscholar   +1 more source

Computational Simulations of Metal–Organic Frameworks to Enhance Adsorption Applications

open access: yesAdvanced Materials, EarlyView.
This review highlights the significance of molecular simulations in expanding the understanding of metal–organic frameworks (MOFs) and improving their gas adsorption applications. The historical development and implementation of molecular simulations in the MOF field are given, high‐throughput computational screening studies used to unlock the ...
Hilal Daglar   +3 more
wiley   +1 more source

A BORON COMPLEX DESIGNED FOR FLUORINE-18 LABELING AIMING FOR PET IMAGING APPLICATION

open access: yesHematology, Transfusion and Cell Therapy
Introduction/Justification: Positron emission tomography (PET) is a rapidly expanding clinical modality worldwide due to the availability of compact medical cyclotrons and automated chemistry for the production of radiopharmaceuticals.
Mariana Almeida Figueira   +6 more
doaj  

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