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Recommendations for fluorine-18 production
International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1991Abstract Data for the production of fluorine-18 (t 1/2 = 109.6 min; β + = 100%) are reviewed. The experience of some well-established European centres for positron emission tomography (PET), in the routine production of fluorine-18 for the purpose of labelling radiopharmaceuticals, is described.
Guillaume, Marcel+5 more
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Preparation of carrier-free fluorine-18
The International Journal of Applied Radiation and Isotopes, 1977Abstract A method for the preparation of carrier-free fluorine-18 using a column of hydrous stannic oxide is described. The adsorption and desorption characteristics of the fluoride ion on the column has been investigated using F-18 as a tracer. The present study has confirmed that the fluoride ion is practically completely adsorbed on the column in ...
T.H. Hsieh+3 more
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A cyclotron method for the production of fluorine-18
The International Journal of Applied Radiation and Isotopes, 1966Abstract Fluorine-18 is produced, with yields of up to 40 mc/hr, by the bombardment of water contained in a suitable target held in the external α-particle beam of a 30 MeV cyclotron: a method is described which is in routine use to produce samples for medical research purposes.
John C. Clark, D.J. Silvester
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A NEW SYNTHESIS OF FLUMAZENEL SUITABLE FOR FLUORINE-18 LABELING
Organic Preparations and Procedures International, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
BROGGINI, GIANLUIGI+3 more
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The value of fluorine-18 for scanning bone tumours
Clinical Radiology, 1969The mechanisms of uptake of fluorine and strontium by normal as well as abnormal bone are described and the advantages of fluorine for scanning are emphasized. The scanning technique is discussed and a method for accurate reduction in size of the radiographic image to correspond exactly with that of the scan image is described.
Alice Sams+3 more
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Production of carrier-free fluorine-18
The International Journal of Applied Radiation and Isotopes, 1965Abstract A rapid and effective procedure for the preparation of carrier-free fluorine-18 is described. The F 18 is produced by neutron irradiation of lithium carbonate and is separated by dissolving the material in acid and distilling off the hydrogen fluoride solution.
C.C. Thomas, R.C. Kerns, J.A. Sondel
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Fluorine-18 Labeling of Peptides and Proteins
2006The pool of promising peptides worthy of investigation and evaluation for clinical use is continuously filled from different sources. Driven by the promising results obtained with peptides addressing somatostatin-2 receptor positive (sst2+) neuroendocrine tumours, other peptides targeting further receptor systems are being studied and evaluated ...
Margret Schottelius, Hans-Jürgen Wester
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Synthesis of fluorine-18 labeled 21-fluoroprogesterone
Steroids, 197721-Fluoroprogesterone has been synthesized by the nucleophilic displacement of the mesyl group of the 21-hydroxypregn-4-ene-3,20-dione 21-methanesulfonate by fluoride ion, as formed from the solvolysis of potassium fluoride in acetonitrile, using 18-Crown-6 as the catalyst.
Carol A. Marino, Larry A. Spitznagle
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Fluorine-18 Fluorodeoxyglucose Uptake in the Retractile Testis
Clinical Nuclear Medicine, 1999A 51-year-old man with a palpable mass in his right inguinal region had fluorine-18 fluorodeoxyglucose (F-18 FDG) whole-body positron emission tomography (PET) in our cancer screening program. FDG accumulated in the mass, suggesting a metabolically active lesion that was likely malignant.
Atsushi Kubo+5 more
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Synthesis of the fluorine-18 labeled inhalation anesthetics
Applied Radiation and Isotopes, 1994Fourteen compounds (fluoroalkanes and fluoroethers), including the two most utilized inhalation anesthetics Isoflurane (CF3CHClOCF2H) and Halothane (CF3CHBrCl), have been labeled with fluorine-18 via a facile 18F-for-19F exchange reaction. The compounds include ten inhalation anesthetics which span a ten-fold range in potency and four structurally ...
Robert J. Nickles+4 more
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