18FDG production in a PET imaging using a proton flux produced by D-D fusion reaction
Basic & Clinical Cancer Research, 2022 Fluorine 18-deoxyglucose (18FDG) is often used in Positron Emission Tomography (PET). PET imaging is one of the useful tool which is used to cancer detection and management. PET growth is limited due to problems that depend on the production of Fluorine-
Nasrin Niknam +2 more
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Optimization of Automated Solid Phase Extraction-based Synthesis of [18F]Fluorocholine
Korean Journal of Clinical Laboratory Science, 2023 [18F]Fluorocholine is a radiopharmaceutical used non-invasively in positron emission tomography to diagnose parathyroid adenoma, prostate cancer, and hepatocellular carcinoma by evaluating the choline metabolism. In this study, a radiolabeling method for
Jun Young PARK +2 more
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Automated sulfur-[18F]fluoride exchange radiolabelling of a prostate specific membrane antigen (PSMA) targeted ligand using the GE FASTlab™ cassette-based platform [PDF]
, 2023 Sulfur-[18F]fluoride exchange radiochemistry is a rapid and convenient method for incorporating fluorine-18 into biologically active molecules. We report a fully automated radiolabelling procedure for the synthesis of a [18F]SO3F-bearing prostate ...
Aboagye, Eric O. +10 more
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Silicon-[18F]Fluorine Radiochemistry: Basics, Applications and Challenges
Applied Sciences, 2012 Silicon-[18F]fluorine (Si-18F) radiochemistry has recently emerged alongside other unconventional approaches such as aluminum-18F and boron-18F based labeling strategies, reshaping the landscape of modern 18F-radiochemistry. All these novel methodologies
Carmen Wängler +5 more
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Expanding the 18F-radiochemical space: synthesis and applications of 1,1-18F-difluorinated alkenes [PDF]
, 2019 The synthesis of 18F-perfluorinated motifs from [18F]fluoride is a non-trivial undertaking as highlighted by the few methods and range of motifs that are known.
Tredwell, Matthew
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Cross-Coupling Reactions as Valuable Tool for the Preparation of PET Radiotracers
Molecules, 2011 The increasing application of positron emission tomography (PET) in nuclear medicine has stimulated the extensive development of a multitude of new radiotracers and novel radiolabeling procedures with the most prominent short-lived positron emitters ...
Marc Pretze +2 more
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Fluorine-18-Labeled Fluorescent Dyes for Dual-Mode Molecular Imaging
Molecules, 2020 Recent progress realized in the development of optical imaging (OPI) probes and devices has made this technique more and more affordable for imaging studies and fluorescence-guided surgery procedures.
Maxime Munch +2 more
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Diagnostics, 2021 Scandium-44 has been proposed as a valuable radionuclide for Positron Emission Tomography (PET). Recently, scandium-43 was introduced as a more favorable option, as it does not emit high-energy γ-radiation; however, its currently employed production ...
Thiago V. M. Lima +6 more
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Molecules, 2018 Cyclooxygenase 2 (COX-2) is an inducible enzyme responsible for the conversion of arachidonic acid into the prostaglandins, PGG2 and PGH2. Expression of this enzyme increases in inflammation.
Michelle Y. Cortes-Salva +8 more
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Evaluation of Organo [18F]Fluorosilicon Tetrazine as a Prosthetic Group for the Synthesis of PET Radiotracers [PDF]
, 2020 Fluorine-18 is the most widely used positron emission tomography (PET) radionuclide currently in clinical application, due to its optimal nuclear properties. The synthesis of 18F-labeled radiotracers often requires harsh reaction conditions, limiting the
Airaksinen, Anu J. +5 more
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