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Electrophilic Aromatic Fluorination with Fluorine: meta‐Directed Fluorination of Anilines.
ChemInform, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
J.P. Alric +3 more
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α-Fluorination of carbonyls with nucleophilic fluorine
Nature Chemistry, 2019Given the unique properties of fluorine, and the ability of fluorination to change the properties of organic molecules, there is significant interest from medicinal chemists in innovative methodologies that enable the synthesis of new fluorinated motifs.
Pauline Adler +5 more
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Current Pharmaceutical Design, 1970
Abstract: Following the discovery of nalidixic acid in 1962, numerous structural modifications have been made to the quinolone nucleus to increase antimicrobial activit> and improve pharmacokinetic performance. A major advance occured during the 1980\ with the discovery that a fluorine at position-6 conferred broad and potent antimicrobial activity,
M, Kidwai, P, Misra, R, Kumar
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Abstract: Following the discovery of nalidixic acid in 1962, numerous structural modifications have been made to the quinolone nucleus to increase antimicrobial activit> and improve pharmacokinetic performance. A major advance occured during the 1980\ with the discovery that a fluorine at position-6 conferred broad and potent antimicrobial activity,
M, Kidwai, P, Misra, R, Kumar
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Organic & Biomolecular Chemistry, 2022
Fluorinated fluorenones can be elaborated to polyhalogenated dibenzochrysenes in 4 steps.
Cody F. Dickinson +2 more
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Fluorinated fluorenones can be elaborated to polyhalogenated dibenzochrysenes in 4 steps.
Cody F. Dickinson +2 more
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Dalton Transactions, 2015
Welcome to this themed issue of Dalton Transactions entitled ‘Fluorine’.
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Welcome to this themed issue of Dalton Transactions entitled ‘Fluorine’.
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Corrosion by Fluorine and Fluorine Compounds
Corrosion, 1952The extreme reactivity of fluorine paradoxically brings to its compounds their most attractive properties—resistance to chemical attack. Because it tends to displace other elements and because no other element is sufficiently reactive to displace fluorine, fluorine compounds become chemically inert.
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1977
The preventive effect of fluorine against dental caries has been well-known for a long time. In recent years the addition of fluorine to the public water supply of communities has, therefore, become increasingly frequent. Since, however, the borderline between toxic and beneficial intake as regards the prevention of dental caries is very narrow, the ...
J, Kumpulainen, P, Koivistoinen
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The preventive effect of fluorine against dental caries has been well-known for a long time. In recent years the addition of fluorine to the public water supply of communities has, therefore, become increasingly frequent. Since, however, the borderline between toxic and beneficial intake as regards the prevention of dental caries is very narrow, the ...
J, Kumpulainen, P, Koivistoinen
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Investigation of fluorination by atomic fluorine
Journal of Fluorine Chemistry, 1991Abstract The process of fluorination of uranium tetrafluoride by atomic fluorine has been investigated on a closed circulation facility. The concentration of atomic fluorine in the flux was estimated using thermocouples. The ratio of fluorination at different distances from the atomic fluorine source was determined.
P.E. Erilov, V.V. Titov, V.F. Serik
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Fluorinations Not Using Fluorine Gas
2022The introduction of fluorine in pharmaceuticals and agrochemicals can be highly advantageous. The substitution of one or just a few hydrogen atoms by fluorine can dramatically alter a compounds acidity/basicity and lipophilicity, which may result in an improvement of its biological and/or pharmaceutical properties.
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Chemistry - A European Journal, 2001
Recent developments in fluorination of fullerenes coupled with HPLC separation have permitted the isolation and subsequent structural characterisation of many derivatives, a number of which have novel and unexpected structures. The good solubility of fluorofullerenes, high reactivity towards nucleophiles and enhanced dienophilicity of the unsubstituted
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Recent developments in fluorination of fullerenes coupled with HPLC separation have permitted the isolation and subsequent structural characterisation of many derivatives, a number of which have novel and unexpected structures. The good solubility of fluorofullerenes, high reactivity towards nucleophiles and enhanced dienophilicity of the unsubstituted
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