Results 131 to 140 of about 152,276 (162)

New insights into radiolabelled siderophores for molecular imaging of bacterial infections. [PDF]

Npj Imaging
Dvorakova Bendova K, Krasulova K, Neuzilova B, Hajduch M, Petrik M.   +4 more
europepmc   +1 more source

Radiosynthesis and Evaluation of [¹⁸F]FEHSP990 as Novel PET Tracer for Hsp90 PET Imaging. [PDF]

J Labelled Comp Radiopharm
Cools R, Vermeulen K, Celen S, Leitao RCF, Bormans G.   +4 more
europepmc   +1 more source

Fluorine-18 Fluorothymidine: A New Positron Emission Radioisotope for Renal Tumors

Clinical Nuclear Medicine, 2006
Fluorine-18 fluorothymidine (F-18 FLT) is a radioisotope based on the nucleic acid thymidine and has emerged as an important tracer that mirrors cellular proliferation in positron emission tomography (PET) studies. Early studies in human tumors have been promising.
Nathan, Lawrentschuk, A M T, Poon, A M, Scott   +2 more
openaire   +3 more sources

Analysis of metal radioisotope impurities generated in [18O]H2O during the cyclotron production of fluorine-18

Applied Radiation and Isotopes, 2006
We show the separation of metal radioisotope impurities using capillary electrophoresis (CE). The methodology used is an improvement of existent protocols for separation of stable metal ions. Production of fluorine-18 using [(18)O]H(2)O-enriched water encased in a titanium target body results in the production of several metal radioisotope impurities ...
J M, Gillies, N, Najim, J, Zweit
openaire   +3 more sources

[Radioisotope study of the effect of fluorine on the mineral and protein metabolism in teeth and bones].

Stomatologiia, 1967
Kolesnik Ag
openaire   +2 more sources

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Phosphonate-Based Aza-Macrocycle Ligands for Low-Temperature, Stable Chelation of Medicinally Relevant Rare Earth Radiometals and Radiofluorination.

Journal of the American Chemical Society
Radioisotopes of fluorine (18F), scandium (43/44Sc, 47Sc), lutetium (177Lu), and yttrium (86Y, 90Y) have decay properties ideally suited for targeted nuclear imaging and therapy with small biologics, such as peptides and antibody fragments.
Jennifer N. Whetter, Dariusz Śmiłowicz, K. Becker, E. Aluicio‐Sarduy, Cormac A A Kelderman, Angus J Koller, Owen M Glaser, Axia Marlin, S. Ahn, Margarita N. Kretowicz, Jonathan W. Engle, Eszter Boros   +11 more
semanticscholar   +1 more source

Development of Peptide-Based Probes for Molecular Imaging of the Postsynaptic Density in the Brain.

Journal of Medicinal Chemistry
The postsynaptic density (PSD) comprises numerous scaffolding proteins, receptors, and signaling molecules that coordinate synaptic transmission in the brain. Postsynaptic density protein 95 (PSD-95) is a master scaffold protein within the PSD and one of
E. F. A. Fernandes, M. Palner, N. Raval, Troels E Jeppesen, Daniela Danková, Simone L Bærentzen, Christian Werner, Janna Eilts, H. Maric, S. Doose, Sanjay Sagar Aripaka, S. Kaalund, Susana Aznar, Andreas Kjaer, Andreas Schlosser, Linda M Haugaard-Kedström, G. Knudsen, M. Herth, Kristian Stro Mgaard   +18 more
semanticscholar   +1 more source

Transition-Metal-Mediated Radiohalogenation using Aryl Boron Reagents

Synthesis
Biomolecules labeled with radioisotopes of iodine and fluorine play a major role in science and medicine, with a range of applications including molecular imaging of disease, as radiopharmaceuticals for therapy and as tools for drug discovery. Due to the
Valeria K. Burianova, Holly McErlain, Andrew Sutherland   +2 more
semanticscholar   +1 more source

A metal-free route to PET probes

Science, 2019
Radiotracer Chemistry Positron emission tomography (PET) is a widely used imaging technique for medical diagnostics and pharmaceutical development. As the name implies, it requires tracers that emit positrons, typically through labeling with fluorine or ...
J. Yeston
semanticscholar   +1 more source

Plasma pharmacokinetic evaluation of cytotoxic agents radiolabelled with positron emitting radioisotopes

Cancer Chemotherapy and Pharmacology, 2008
A. Saleem, E. Aboagye, J. Matthews, P. Price   +3 more
semanticscholar   +1 more source