This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang +11 more
wiley +1 more source
Filling the gap: electrochemical access to the missing group IV HfO-based rocksalt compound.
Bechteler C, Todd RI.
europepmc +1 more source
Vacancy-mediated ultrafast oxide-ion conduction in excess-oxygen Sillén oxybromides. [PDF]
Kanenori Y +10 more
europepmc +1 more source
Ferroelectric Devices for In‐Memory and In‐Sensor Computing
Inspired by biological systems, in‐memory and in‐sensor computing overcome von Neumann bottlenecks. Ferroelectric devices can mimic synaptic functions and sense stimuli like light or force, therefore are ideal for these paradigms. This review introduces the ferroelectric devices applied for in‐memory and in‐sensor computing, covering their structures ...
Hong Fang +5 more
wiley +1 more source
Pu-Doping-Induced Weberite-like Local Motifs and Enhanced Immobilization in Gd<sub>2</sub>Zr<sub>2</sub>O<sub>7</sub> Pyrochlore: A DFT + <i>U</i> Study. [PDF]
Yang L, Zhao F, Wang H, Ni Y, Lu X.
europepmc +1 more source
Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung +7 more
wiley +1 more source
High-Temperature Mechanical Characterization of CeO<sub>2</sub> as a Ceramic Surrogate Fuel Based on FIB and Nanoindentation. [PDF]
Si J +6 more
europepmc +1 more source
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng +9 more
wiley +1 more source
Disordered vacancy-isolated Ce-Gd-O clusters achieve exceptional low-temperature oxygen-ion conductivity for fuel cells. [PDF]
Pang S +13 more
europepmc +1 more source
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen +15 more
wiley +1 more source

