Results 231 to 240 of about 12,098 (304)

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

A Review on the Evolution of Thermal and Environmental Barrier Coating Systems and Their High-Temperature Degradation Mechanisms in Advanced Aero-Engines. [PDF]

Materials (Basel)
Ren S, Sun Y, Yan H, Zhang X, Bao Y, Lv K.   +5 more
europepmc   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

A bond valence sum method to identify potential new fluoride ion conductors. [PDF]

J Appl Crystallogr
Shaw R, Pérez GE, Playford H, Hull S.
europepmc   +1 more source

High-Temperature Superconductivity of Thermodynamically Stable Fluorite-Type Hydrides at Ambient Pressure. [PDF]

Adv Sci (Weinh)
Huang H, Yan X, Wang M, Du M, Song H, Liu Z, Duan D, Cui T, Wei X.   +8 more
europepmc   +1 more source

Total Oxidation of Toluene over Pt/CeO₂-Fe₂O₃ Catalysts: Role of CeO₂/Fe₂O₃ Ratio. [PDF]

Nanomaterials (Basel)
Savel'eva A, Ponizovnaya D, Mamontov G.
europepmc   +1 more source

The urgent electrolyte sustainability challenges for electric vehicle batteries. [PDF]

Nat Commun
Burton TF, Gómez Urbano JL, Zhu Y, Balducci A, Fontaine O.   +4 more
europepmc   +1 more source

Integrated radiometric and mineralogical investigation of radioactive mineralization in the El-Erediya Shear Zone, Eastern Desert, Egypt. [PDF]

Sci Rep
Rageh H, Abdel-Hakeem M, El-Tahir M, Zeid EA, Milano M, Abbas MA.   +5 more
europepmc   +1 more source

On the Impurities in Fluorites (Studies on the Fluorites from Japan, II)

On the Impurities in Fluorites (Studies on the Fluorites from Japan, II)
openaire