Results 61 to 70 of about 12,098 (304)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

REY and Trace Element Chemistry of Fluorite from Post-Variscan Hydrothermal Veins in Paleozoic Units of the North German Basin

Geosciences, 2018
Hydrothermal fluorites from Paleozoic sedimentary rocks and volcanic units in the North German Basin (NGB) have been investigated to create a petrographic and geochemical inventory—with particular focus on strategic elements such as rare earth ...
Patrick Nadoll, Meike Rehm, Florian Duschl, Reiner Klemd, Dennis Kraemer, Marta Sośnicka   +5 more
doaj   +1 more source

Nickel-Containing Ceria-Zirconia Doped with Ti and Nb. Effect of Support Composition and Preparation Method on Catalytic Activity in Methane Dry Reforming

Nanomaterials, 2020
Nickel-containing mixed ceria-zirconia oxides also doped by Nb and Ti have been prepared by a citrate route and by original solvothermal continuous flow synthesis in supercritical alcohols.
Mikhail Simonov, Yulia Bespalko, Ekaterina Smal, Konstantin Valeev, Valeria Fedorova, Tamara Krieger, Vladislav Sadykov   +6 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Fluorite flotation separation from calcite using guar gum as a depressant

Results in Engineering
:: As a strategically significant non-metallic mineral resource, fluorite faces considerable challenges in its flotation separation from associated calcite due to their highly similar surface properties and nearly identical responses to conventional ...
Junqi Jiang, xinyang yu, Feng Wu, Yanbo Zhong, Guichun He, Zhilin Liu   +5 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Fluorite - 3D models - decimated

Fluorite - 3D models ...
Kellie, Adam
core   +1 more source

Fluorite Daylight 5600K

, 2023
Beautiful green fluorite sample but fluoresces purple under shortwave UV light.
Valerio, Juliana
core