Results 131 to 140 of about 131,040 (312)

Tumour‐informed workflow to use ctDNA as a biomarker for risk of recurrence in head and neck cancer patients post‐treatment

VIEW, EarlyView.
Our study presents a tumour‐informed circulating tumour DNA (ctDNA) workflow designed to enhance the detection of recurrence in head and neck cancer patients, addressing key challenges such as low ctDNA tumour fractions and tumour heterogeneity. Abstract Circulating tumour DNA (ctDNA) is a promising minimally invasive biomarker for monitoring treatment
Xiaomin Huang, Paul Leo, Mhairi Clout, Lynn Fink, Jonathan Ellis, Brett G. M. Hughes, Lizbeth Kenny, Sarju Vasani, Chamindie Punyadeera   +8 more
wiley   +1 more source

Detection of Hepatic Metastasis from Early Delayed Images of Modified Dual-Time-Point F-18 FDG PET/CT Images in a Patient with Breast Cancer

Diagnostics
We present a rare case of focal F-18-2-fluoro-2-deoxyglucose (FDG) uptake in the liver observed during a modified dual-time-point F-18 FDG positron emission tomography (PET)/computed tomography (CT), so-called early delayed scanning, in a 53-year-old ...
Ji Young Lee, Hee-Sung Song
doaj   +1 more source

Surveillance After Pelvic Exenteration: A Systematic Review of Oncological and Functional Follow‐Up

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Surveillance following cancer surgery with curative intent serves the purpose of permitting early detection of recurrent disease in addition to monitoring and management of post‐resection functional sequelae. Although recommendations exist for most primary cancers, in the context of radical or re‐operative surgery such as pelvic ...
Adrian Hang Yue Siu, Konrad Joseph, Daniel Steffens, Sharon Carey, Michael Solomon, Cherry Koh   +5 more
wiley   +1 more source

Prognostic role of PET/CT volumetric parameters in paediatric Hodgkin lymphoma: A systematic review and expert recommendations from the International SEARCH for CAYAHL Group

British Journal of Haematology, EarlyView.
A visual overview of the key findings from the 35 papers included in this systematic review evaluating the use of PET volumetric parameters in children, adolescents and young adults with Hodgkin lymphoma. Summary In adults with classic Hodgkin lymphoma (cHL), metabolic tumour volume (MTV) is valuable for risk stratification.
S. Claire Gowdy, Jamie E. Flerlage, Jennifer Seelisch, Monica Palese, Tyler Bradshaw, Sharon M. Castellino, Steve Cho, Karin Dieckmann, Bradford S. Hoppe, Scott Howard, Kara M. Kelly, Lars Kurch, Hollie A. Lai, Egesta Lopci, John T. Lucas Jr., Christine Mauz‐Körholz, Kathleen M. McCarten, Neeta Pandit‐Taskar, Heiko Schöder, Jonas Steglich, Dietrich Stoevesandt, Stephan D. Voss, Sarah A. Milgrom   +22 more
wiley   +1 more source

Immunoprofiling, sex‐ and age‐related determinants of treatment response in paediatric, adolescent and young adult Hodgkin lymphoma

British Journal of Haematology, EarlyView.
Multimodal integration of sex‐ and age‐related immune‐gene signatures with baseline tumor burden (TMTV1) improves prediction of treatment response in adolescents and young adults with classical Hodgkin lymphoma. Summary The study investigates how sex and age influence treatment response in paediatric, adolescent and young adult (AYA) classical Hodgkin ...
Valli De Re, Egesta Lopci, Giulia Brisotto, Caterina Elia, Angelo Vitullo, Veronica Paduano, Mariangela De Zorzi, Lara Mussolin, Paola Quarello, Simona Bianchi, Salvatore Buffardi, Alberto Garaventa, Paola Muggeo, Marta Pillon, Alessandra Sala, Luciana Vinti, Emanuele d'Amore, Christine Mauz‐Korholz, Maurizio Mascarin, on behalf of the AIEOP Hodgkin's Lymphoma Study Group, Alberto Garaventa, Alessandra Sala, Antonella Sau, Assunta Tornesello, Daniela Galimberti, Domenico Sperlì, Elena Facchini, Eulalia Galea, Federico Verzegnassi, Fiorina Giona, Francesca Rossi, Fulvio Porta, Irene D’Alba, Katia Perruccio, Luciana Vinti, Marco Zecca, Marta Pillon, Massimo Provenzi, Maurizio Bianchi, Maurizio Mascarin, Monica Cellini, Nadia Vacca, Paola Muggeo, Patrizia Bertolini, Piero Farruggia, Raffaella De Santis, Roberta Pericoli, Rosamaria Mura, Salvatore Buffardi, Salvatore D’Amico, Sayla Bernasconi, Simona Rinieri, Simone Cesaro, Tommaso Casini, Valerio Cecinati   +54 more
wiley   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source

Multimodal machine learning for surgical decision support in epilepsy: Current evidence and translational gaps

Epilepsia, EarlyView.
Abstract Objective This systematic review synthesizes evidence on multimodal machine learning (ML) decision support systems for epilepsy surgery focusing on postsurgical outcome prediction, with emphasis on methodological quality and implications for clinical practice.
Mattia Mercier, Luca de Palma, Nicola Specchio   +2 more
wiley   +1 more source

Utility of stereo‐electroencephalography in patients with bilateral independent/unclear scalp electroencephalographic seizure onset

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to determine whether bilateral independent or unclear (BI/U) scalp electroencephalographic (EEG) ictal onset patterns may predict the diagnostic yield of stereo‐electroencephalography (SEEG) and inform surgical decision‐making in patients with focal drug‐resistant epilepsy.
Aayesha J. Soni, M. Claudia Burbano, R. Grace Couper, Poul H. Espino, John A. L. Perez, Amit Persad, Khalid Alorabi, Poornima N. Nambiar, Arun Thurairajah, David Diosy, Michelle‐Lee Jones, Ana Suller Marti, Keith W. MacDougall, Jonathan C. Lau, David A. Steven, Jorge G. Burneo, Giovanni Pellegrino   +16 more
wiley   +1 more source

Fatal familial insomnia that begins with unconsciousness: A case report

Sleep Research, EarlyView.
Wenyan Liu, Xinyue Xing, Xiaoming Wang, Xuqian Liu, Mingyue Liu, Wei Shang, Zhaohong Xie   +6 more
wiley   +1 more source