Results 91 to 100 of about 12,307 (185)

Standardization and Modification of Fluorometric Method of Histamine Assaying in Whole Blood

open access: yesپزشکی بالینی ابن سینا, 1996
Histamine (Hm), formed during decarboxylation of L-histidine by the action of L-histidine decarboxylase, a pyridoxal phophate dependent enzyme, is one of the main mediator in such allergic diseases as asthma, urticaria and hay fever.
Tirang Neyestani   +3 more
doaj  

Consequences of CRISPR‐Cas9‐Mediated Stromelysin‐1 Knockout in Pancreatic Islet Microvascular Endothelial Cells

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT The integrity of the pancreatic islet microvasculature is critical for endocrine function, yet it is progressively compromised by glucotoxicity in diabetes. While matrix metalloproteinases are implicated, the role of stromelysin‐1 as a potential upstream driver of endothelial dysfunction remains poorly defined.
Bing Wang   +9 more
wiley   +1 more source

Fluorescent proteins: A journey from the cell to extreme environments in material science

open access: yesPhotochemistry and Photobiology, Volume 102, Issue 2, Page 290-302, March/April 2026.
Applications of proteins and microorganisms as tools or effectors in material science. Abstract This review presents the progression from the use of fluorescent proteins (FPs) and chromoproteins as bioimaging labels and sensors to the strategic engineering of their properties for robust functionality in synthetic and non‐biological environments ...
Bianca Menchicchi   +3 more
wiley   +1 more source

Distinct profiles of mitochondrial bioenergetics and redox balance in left atrial and ventricular myocardium in the healthy rat heart

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 1058-1068, 1 March 2026.
Abstract The left ventricle (LV) is the primary pumping chamber of the heart, generating high systolic pressure to sustain systemic circulation. LV contractile dysfunction is a hallmark of various cardiovascular diseases and is associated with mitochondrial dysfunction, characterised by decreased oxidative phosphorylation (OXPHOS) capacity and ...
Tingting Fang   +3 more
wiley   +1 more source

Voltage-clamp fluorometry to record flow-activated PIEZO1 currents and fluorometric signals

open access: yesSTAR Protocols
Summary: PIEZO channels sense mechanical forces through conformational rearrangements of a mechanosensory domain called blade. To probe these rearrangements in real time, we have inserted conformational-sensitive cyclic-permuted GFP into several ...
Tharaka Wijerathne, Jerome Lacroix
doaj   +1 more source

Unraveling the Folding Dynamics of DNA Origami Structures. [PDF]

open access: yesSmall
Mohammadi-Zerankeshi M   +4 more
europepmc   +1 more source

Systematic analysis of COVID-19 mRNA vaccines using four orthogonal approaches demonstrates no excessive DNA impurities. [PDF]

open access: yesNPJ Vaccines
Achs A   +14 more
europepmc   +1 more source

Targeting transglutaminase 2: pathways to celiac disease therapies. [PDF]

open access: yesGastroenterol Rep (Oxf)
Endrizzi A   +5 more
europepmc   +1 more source

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