Results 31 to 40 of about 17,962 (220)

Efflux-Mediated Resistance in Enterobacteriaceae: Recent Advances and Ongoing Challenges to Inhibit Bacterial Efflux Pumps

open access: yesAntibiotics
Efflux is one of the key mechanisms used by Gram-negative bacteria to reduce internal antibiotic concentrations. These active transport systems recognize and expel a wide range of toxic molecules, including antibiotics, thereby contributing to reduced ...
Florent Rouvier   +3 more
doaj   +1 more source

Cumulative glycaemia as measured by lens fluorometry: association with retinopathy in type 2 diabetes

open access: yes, 2010
The aim of this study was to assess the association between lifelong cumulative glycaemia estimated by lens fluorometry and the presence of retinopathy in individuals with type 2 ...
I. C. Munch   +13 more
core   +1 more source

Influence of seeding rates on the quantum yield of photosynthesis for some field crops

open access: yesТруды по прикладной ботанике, генетике и селекции
Background. Photosynthesis is one of the most important physiological processes in plants, affecting the productivity of agrocenoses. Creating conditions for crops to absorb and convert solar energy as effectively as possible can be a means of increasing
K. S. Panchenko   +3 more
doaj   +1 more source

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

open access: yesAdvanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu   +11 more
wiley   +1 more source

Fluorescence Studies of Selected 2-Alkylaminopyrimidines

open access: yesMolecules, 2004
The reactions of 2-chloropyrimidine with methylamine, ethylamine and piperidine gave the corresponding 2-N-methylamino-, 2-N-ethylamino- and 2N- piperidinopyrimidines, respectively.
B. K. Low   +4 more
doaj   +1 more source

Multiple mechanisms contribute to fluorometry signals from the voltage-gated proton channel

open access: yesCommunications Biology, 2022
Fluorometry signals indicating conformational change in an ion channel are generated by quenching amino acids and lipid effects during movement of the dye relative to the plane of the membrane.
Ferenc Papp   +10 more
doaj   +1 more source

Critical evaluation of heat extraction temperature on soluble microbial products (SMP) and extracellular polymeric substances (EPS) quantification in wastewater processes

open access: yesWater Science and Technology, 2022
While soluble microbial products (SMP) and extracellular polymeric substances (EPS) in wastewater bioprocesses have been widely studied, a lack of standard quantification procedures make it difficult to compare results between studies.
Kahao Lim, Prathap Parameswaran
doaj   +1 more source

A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology

open access: yesAdvanced Science, EarlyView.
A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao   +34 more
wiley   +1 more source

Determination of Extra Virgin Olive Oil Adulteration Using Laser Induced Fluorometry – Chlorophyll Relative Intensity Method

open access: yesActa Technologica Agriculturae
A new method has been proposed for detecting the potential adulteration of extra virgin olive oil with processed sunflower oil. This method is based on analysing the laser-induced fluorescence (LIF) spectra of samples.
Kosor Tihomir   +5 more
doaj   +1 more source

The Histidine 382 Residue Influences the Thermal Stability and Binding Propensity of the E2 Domain of Amyloid Precursor Protein

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The E2 domain of amyloid precursor protein (APP_E2) plays a central role in the protein's function. We reinvestigate how the missense mutation, ΔH382L, affects the domain's thermal stability and ligand binding propensity through differential scanning fluorometry.
Sphamandla Ndlovu   +4 more
wiley   +1 more source

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