Results 251 to 260 of about 134,982 (313)
NAT10‐Mediated ac4C Modification of circANKRD12 Reprograms the Tumor Microenvironment
Advanced Science, EarlyView.NAT10‐dependent acetylation of circANKRD12 drives translation of the circANKRD12_354aa protein, which binds HDAC2 to stabilize c‐Myc via deubiquitination, promoting multiple myeloma (MM) cell proliferation. Concurrently, the circANKRD12‐HDAC2 axis suppresses H3ac‐mediated transcription of IFN‐γ, TNF‐α, and GZMB in NK cells, leading to NK cell ...
Jiale Zhang +8 more
wiley +1 more source
A demethylation-activated fluorescent DNA aptamer strategy for visualising DNA alkylation repair in living cells. [PDF]
Chem SciLuan X +7 more
europepmc +1 more source
Advanced Science, EarlyView.Ascorbic Acid‐Engineered Interface Enables Universal DNA Functionalization on Gold Nanoparticles: Attenuating electrostatic repulsion and leveraging synergistic hydrogen‐bonding interactions significantly lowers the kinetic barrier for DNA adsorption, enabling rapid and sequence‐general functionalization of non‐thiolated DNA‐requiring only a single ...
Guangping Li +9 more
wiley +1 more source
DNA-hybridization on gold nanospheres: a dual-fluorescence investigation of surface loading and strand length effects. [PDF]
J Biomed OptStoia D +7 more
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Advanced Science, EarlyView.SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu +8 more
wiley +1 more source
A Standardized Prism-Based TIRF Platform for Quantitative Single-Molecule Fluorescence Studies of Biomolecular Dynamics. [PDF]
Biosensors (Basel)Patra A +4 more
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Reconstruction of Fluorophore Concentration Variation in Dynamic Fluorescence Molecular Tomography
IEEE Transactions on Biomedical Engineering, 2015 Dynamic fluorescence molecular tomography (DFMT) is a potential approach for drug delivery, tumor detection, diagnosis, and staging. The purpose of DFMT is to quantify the changes of fluorescent agents in the bodies, which offer important information ...
Xuanxuan Zhang, Simin Zuo, Junwei Shi
exaly +2 more sources
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Use of Intraoperative Fluorophores
Neurosurgery Clinics of North America, 2021Fluorescence-guided surgery provides surgeons with improved visualization of tumor tissue in the operating room to allow for maximal safe resection of brain tumors. Multiple fluorescent agents have been studied for fluorescence-guided surgery. Both nontargeted and targeted fluorescent agents are currently being used for glioblastoma multiforme ...
Alexander J, Schupper +1 more
openaire +2 more sources
Photoactivatable fluorophores for bioimaging applications
Colloidal Nanoparticles for Biomedical Applications XVIII, 2023Photoactivatable fluorophores provide the opportunity to switch fluorescence on exclusively in a selected area within a sample of interest at a precise interval of time. Such a level of spatiotemporal fluorescence control enables the implementation of imaging schemes to monitor dynamic events in real time and visualize structural features with ...
Yang Zhang +4 more
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Benzobisimidazole Cruciform Fluorophores
The Journal of Organic Chemistry, 2015A series of 11 cross-conjugated cruciform fluorophores based on a benzobisimidazole nucleus has been synthesized and characterized. Like in their previously reported benzobisoxazole counterparts, the HOMOs of these new fluorophores are localized along the vertical bisethynylbenzene axes, while their LUMOs remain relatively delocalized across the ...
Ha T M, Le +2 more
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