Results 1 to 10 of about 6,780 (162)

Exploring the Population Pharmacokinetic and Pharmacogenetics Characteristics of Flurbiprofen Isomers in Selective Joint Replacement Patients with Postoperative Pain [PDF]

Drug Design, Development and Therapy
Han Yao,1,* Xingxian Luo,2,* Jinjie Yuan,3 Hong Zhang,1 Haiyan An,1 Yi Feng1 1Department of Anesthesiology, Peking University People’s Hospital, Beijing, People’s Republic of China; 2Department of Pharmacy, Peking University People’s ...
Yao H, Luo X, Yuan J, Zhang H, An H, Feng Y   +5 more
doaj   +2 more sources

Efficacy of Locally Applied Flurbiprofen in Sore Throat Treatment: A Scoping Review [PDF]

Biomedicines
Background and Objectives: Sore throat is a common symptom that, due to its heterogeneous etiology and diverse clinical presentation, poses challenges for both accurate diagnosis and etiological treatment, making symptomatic therapy essential. Our review
Emili Dragaš, Dejan Tomljenović, Ivan Rašić, Ivana Jurčić Čulina, Lucija Svetina, Goran Geber, Davor Vagić, Andro Košec   +7 more
doaj   +2 more sources

In-depth summary of adverse events associated with Flurbiprofen: A real-world pharmacovigilance study from 2004 to 2024 using the FAERS database. [PDF]

PLoS ONE
BackgroundFlurbiprofen, as a widely used nonsteroidal anti-inflammatory drug (NSAID), is commonly employed to relieve mild to moderate pain and inflammation.
Chengkai Yang, Qian Guo, Yang Cheng, Fengjing Liu, Hui Zhang, Huaxiang Wang   +5 more
doaj   +2 more sources

The association of intraoperative use of flurbiprofen axetil with the incidence of postoperative shivering in patients undergoing general anesthesia: a retrospective case-control study [PDF]

BMC Anesthesiology
Background Postoperative shivering is a frequent complication following general anesthesia and is associated with various adverse events. Numerous strategies have been explored to prevent postoperative shivering.
Ji-hua Wang, Qi Wang, Hai-xia Zhang, Yan-mei Hu, Yi Liu, Chang-long Qiao, Meng Lv, Jian-bo Wu   +7 more
doaj   +2 more sources

Comparison of oxycodone hydrochloride and flurbiprofen axetil on analgesia in mechanically ventilated patients with respiratory failure in a multicenter study [PDF]

Scientific Reports
The design of this study is to compare the effectiveness of two analgesic drugs in the intervention of pain events for patients on mechanical ventilation.
Zhen-nan Yuan, Yu-juan Xue, Da-wei Li, Hong-sheng Ji, Hai-jun Wang, Fang Cao, Shi-ning Qu, Chu-lin Huang, Hao Wang, Hao Zhang, Xue-zhong Xing   +10 more
doaj   +2 more sources

Flurbiprofen

Reactions Weekly, 2012
Alaa A-M, Abdel-Aziz, Abdullah A, Al-Badr, Gamal Abdel, Hafez   +2 more
europepmc   +5 more sources

Flurbiprofen: Determination of safety profile, analgesic effect, and interaction with lipoic acid in murine [PDF]

Iraqi Journal of Veterinary Sciences, 2023
our study aimed study aimed to detect and investigate the safety profile of flurbiprofen and evaluate the analgesic effects of the tail immersion and writhing tests, as well as its interaction with lipoic acid as an analgesic for visceral pain in mice ...
Naktal M. Alberifki, Ahmed S. Naser
doaj   +1 more source

The Comparison of Plasma and Cerebrospinal Fluid R(−)- and S(+)-Flurbiprofen Concentration After Intravenous Injection of Flurbiprofen Axetil in Human Subjects

Frontiers in Pharmacology, 2021
Background: Flurbiprofen axetil is a prodrug that releases the active substance through enzymatic removal of the ester moiety. It is formulated through encapsulation in a lipid microsphere carrier, and widely used to treat perioperative pain.
Han Yao, Xingxian Luo, Hong Zhang, Haiyan An, Wanyu Feng, Yi Feng   +5 more
doaj   +1 more source

Effects of flurbiprofen on the functional regulation of serotonin transporter and its misfolded mutant

Journal of Pharmacological Sciences, 2022
Flurbiprofen, a nonsteroidal anti-inflammatory drug, reportedly exhibits chemical chaperone activity. Herein, we investigated the role of flurbiprofen in regulating serotonin transporter (SERT) function via membrane trafficking.
Haruki Hirakawa, Kei Taguchi, Seiya Murakawa, Masaya Asano, Soma Noguchi, Satoshi Kikkawa, Kana Harada, Naoko Adachi, Takehiko Ueyama, Izumi Hide, Shigeru Tanaka, Norio Sakai   +11 more
doaj   +1 more source

Flurbiprofen used in one-lung ventilation improves intraoperative regional cerebral oxygen saturation and reduces the incidence of postoperative delirium

Frontiers in Psychiatry, 2022
BackgroundWe previously demonstrated that flurbiprofen increased arterial oxygen partial pressure and reduced intrapulmonary shunts. The present study aims to investigate whether flurbiprofen improves intraoperative regional cerebral oxygen saturation ...
Liang Shen, Liang Shen, Jia-qi Chen, Xin-lu Yang, Ji-cheng Hu, Wei Gao, Xiao-qing Chai, Di Wang, Di Wang   +8 more
doaj   +1 more source