Results 91 to 100 of about 14,854 (205)

An Equation for the Prediction of Human Skin Permeability of Neutral Molecules, Ions and Ionic Species [PDF]

, 2017
yesExperimental values of permeability coefficients, as log Kp, of chemical compounds across human skin were collected by carefully screening the literature, and adjusted to 37 °C for the effect of temperature.
Abraham, M.H., Liu, Xiangli, Zhang, K.
core   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, Volume 36, Issue 16, 23 February 2026.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Population pharmacokinetic modeling of flurbiprofen, the active metabolite of flurbiprofen axetil, in Chinese patients with postoperative pain

Journal of Pain Research, 2018
Jingru Zhang,1,2,* Hong Zhang,1,* Libo Zhao,3 Jian Gu,4 Yi Feng,1 Haiyan An1 1Department of Anesthesiology, Peking University People’s Hospital, Beijing 100044, China; 2Department of Pharmacy Administration and Clinical Pharmacy, School of ...
Zhang J, Zhang H, Zhao L, Gu J, Feng Y, An H   +5 more
doaj  

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin‐induced Intestinal Injury by Production of Carboxylesterase EstB

Advanced Science, Volume 13, Issue 12, 27 February 2026.
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao, Qing Li, Xiaowu Bai, Ertao Zhai, Weigang Dai, Yan Qian, Tianhao Zhang, Zhixin Huang, Ziyu Huang, Fangang Meng, Jianhui Chen, Tao Zuo, Shirong Cai, Risheng Zhao   +13 more
wiley   +1 more source

Separation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using nonaqueous electrolytes. [PDF]

, 1999
peer reviewedThe aim of the present work was to investigate the separation of nonsteroidal anti-inflammatory drugs (NSAIDs: niflumic acid, flufenamic acid, piroxicam, alclofenac, tiaprofenic acid, flurbiprofen, suprofen, ketoprofen, naproxen ...
Bechet, Isabelle, Crommen, Jacques, Fillet, Marianne, Piette, Véronique   +3 more
core   +1 more source

The Impact of Differential Cost Sharing of Non-Steroidal Anti-Inflammatory Agents on the Use and Costs of Analgesic Drugs [PDF]

OBJECTIVE: To estimate the effect of differential cost sharing (DCS) schemes for non-steroidal anti-inflammatory drugs (NSAIDs) on drug subsidy program and beneficiary expenditures.
Adrian R. Levy, Anne M. Holbrook, Bernie J. O'Brien, John K. Marshall, Lisa R. Dolovich, Paul V. Grootendorst   +5 more
core  

Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial [PDF]

, 2012
Aim  To compare the effects of single doses of three oral medications on postoperative pain following instrumentation of root canals in teeth with irreversible pulpitis.
Albashaireh, Breivik, Collins, Dayer, Dionne, Dionne, Doroschak, Georgopoulou, Glennon, Gottesdiener, Haas, Holstein, Imura, Jung, Keiser, Madison, McNicholas, McVerry, Menhinick, Morse, Morse, Nakanishi, Ng, O’Keefe, Penniston, Rosenberg, Roszkowski, Sathorn, Schnitzer, Siqueira, Thun, Torabinejad, Trope, Whitten, Wideman, Wright   +35 more
core   +1 more source

Effect of flurbiprofen sodium on pupillary dilatation during scleral buckling surgery

Indian Journal of Ophthalmology, 1994
Maintenance of pupillary dilatation is necessary for success of scleral buckling procedures. The efficacy of 0.03% flurbiprofen in preventing intraoperative miosis was evaluated by a prospective randomized, double-masked controlled trial of 60 ...
Roysarkar T, Mitra S, Shanmugam M, Ravishankar K, Murugesan Radha   +4 more
doaj  

Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress

EMBO Molecular Medicine, 2014
Endoplasmic reticulum (ER) stress, caused by the accumulation of unfolded proteins, is involved in the development of obesity. We demonstrated that flurbiprofen, a nonsteroidal anti‐inflammatory drug (NSAID), exhibited chaperone activity, which reduced ...
Toru Hosoi, Rie Yamaguchi, Kikuko Noji, Suguru Matsuo, Sachiko Baba, Keisuke Toyoda, Takahiro Suezawa, Takaaki Kayano, Shinpei Tanaka, Koichiro Ozawa   +9 more
doaj   +1 more source

Flurbiprofen ameliorates glucose deprivation-induced leptin resistance

Frontiers in Pharmacology, 2016
Leptin resistance is one of the mechanisms involved in the pathophysiology of obesity. The present study showed that glucose deprivation inhibited leptin-induced phosphorylation of signal transducer and activator of transcription 3 (STAT3) and signal ...
Toru Hosoi, Yuka Suyama, Takaaki Kayano, Koichiro Ozawa   +3 more
doaj   +1 more source