Results 11 to 20 of about 6,780 (162)

Effect of the rs7858836 Single-Nucleotide Polymorphisms of the ASTN2 Gene on Pain-Related Phenotypes in Japanese Women Who Underwent Laparoscopic Gynecologic Surgery. [PDF]

Neuropsychopharmacol Rep
Schematic overview of the study examining the association between the ASTN2 rs7858836 T allele and postoperative pain–related phenotypes in humans. The analysis focuses on the relationship between this genetic variant and postoperative pain intensity as well as analgesic responses.
Inoue R, Nishizawa D, Okahara S, Hara A, Okada H, Hasegawa J, Ebata Y, Nakayama K, Hayashida M, Ikeda K.   +9 more
europepmc   +2 more sources

A Systematic Review of Flurbiprofen 8.75 mg Dose and Risk of Haemorrhagic Events

Frontiers in Pharmacology, 2021
Oral non-steroidal anti-inflammatory drugs (NSAIDs) are known to be associated with an increased risk of bleeding. The NSAID, flurbiprofen, in the form of 8.75 mg lozenge or oromucosal spray is indicated for the symptomatic relief of sore throat. Despite
Sandeep Dhanda, Sandeep Dhanda, Alison Evans, Alison Evans, Debabrata Roy, Debabrata Roy, Vicki Osborne, Vicki Osborne, Adam Townsley, Graça Coutinho, Anuradha Kulasekaran, Saad Shakir, Saad Shakir   +12 more
doaj   +1 more source

Evaluation of the anticonvulsant properties of flurbiprofen in pilocarpine-induced convulsions in mice

Baghdad Journal of Biochemistry and Applied Biological Sciences, 2023
Flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID), possesses non-selective COX inhibition properties. Some NSAIDs exhibits anticonvulsant effects and provide analgesic benefits for seizure patients.
Naktal M. Albrefkani, Ahmed S. Naser
doaj   +1 more source

Assessment of anxiolytic-like effects of acute and chronic treatment of flurbiprofen in murine

Journal of Ideas in Health, 2023
Background: Non-steroidal anti-inflammatory drugs are commonly used medications with atypical pharmacological effects. This aims to evaluate the anxiolytic-like effects of flurbiprofen in rodent models.  Methods: In vivo experimental try was conducted
Ahmed Salah Naser , Naktal Mamish Alberifkani   +1 more
doaj   +1 more source

The Effect of a Local Injection of Flurbiprofen Ester Microspheres on Systemic Inflammatory Model Rats With a Closed Femoral Shaft Fracture

Frontiers in Pharmacology, 2022
Background: Periarticular injections with a combination of local anesthetics, non-steroidal anti-inflammatory analgesics (NSAIDs), and epinephrine are becoming increasingly popular in the perioperative analgesia of artificial joint replacement.
Hui-Ming Peng, Ke Xiao, Wei Zhu, Ying-Jie Wang, Yan-Yan Bian, Wei Wang, Wen-Wei Qian, Xi-Sheng Weng   +7 more
doaj   +1 more source

Efficacy of flurbiprofen axetil for preventing postanesthetic shivering in patients undergoing gynecologic laparotomy surgeries

JA Clinical Reports, 2020
Background Postanesthetic shivering is an unpleasant adverse event in surgical patients. A nonsteroidal anti-inflammatory drug has been reported to be useful in preventing postanesthetic shivering in several previous studies. The aim of this study was to
Atsushi Kotera
doaj   +1 more source

Intra-articular delivery of flurbiprofen sustained release thermogel: improved therapeutic outcome of collagenase II-induced rat knee osteoarthritis

Drug Delivery, 2020
Knee osteoarthritis (OA) is a common degenerative disease. Intra-articular administration of flurbiprofen is frequently employed in clinic to treat OA, while repeated injections are required because of the limited effective duration.
Peinan Li, Haokun Li, Xiaohong Shu, Moli Wu, Jia Liu, Tangna Hao, Hongxia Cui, Lianjie Zheng   +7 more
doaj   +1 more source

Flurbiprofen

, 2006
europepmc   +3 more sources

Penetration of Flurbiprofen from a Locally Applied Sore Throat Lozenge and Spray into Cadaveric Human Pharynx Tissue: A Novel ex vivo Model and Microautoradiography Method

Clinical Pharmacology: Advances and Applications, 2021
Rob Turner,1 Sean Robert Wevrett,1 Suzanne Edmunds,1 Marc Brown,1 Anuradha Kulasekaran,2 Oluwajoba Adegoke,2 John Farrah2 1MedPharm Ltd, Guildford, UK; 2Reckitt Benckiser Healthcare International Ltd., Slough, Berkshire, UKCorrespondence: Oluwajoba ...
Turner R, Wevrett SR, Edmunds S, Brown MB, Kulasekaran A, Adegoke O, Farrah J   +6 more
doaj  

Postoperative short-term use of the nonsteroidal anti-inflammatory drug flurbiprofen did not increase the anastomotic leakage rate in patients undergoing elective gastrointestinal surgery—a retrospective cohort study

Perioperative Medicine, 2022
Background Flurbiprofen has been one of the most commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) in China and other Asian countries for perioperative multimodal analgesia in recent years, yet its association with anastomotic leakage in ...
Huang Nie, Yiming Hao, Xiangying Feng, Lina Ma, Yumei Ma, Zhen Zhang, Xi’an Han, Jian zhong Zhang, Ping Zhang, Qingchuan Zhao, Hailong Dong   +10 more
doaj   +1 more source