Results 31 to 40 of about 6,780 (162)

Biotransformation of the Fluorinated Nonsteroidal Anti‐Inflammatory Pharmaceutical Flurbiprofen in Activated Sludge Results in Accumulation of a Recalcitrant Fluorinated Aromatic Metabolite

Global Challenges, 2019
Flurbiprofen is a fluorinated, nonsteroidal, anti‐inflammatory pharmaceutical with potential application in a wide range of maladies. Currently, there is no information regarding its environmental fate.
Kadir Yanaç, Robert W. Murdoch
doaj   +1 more source

Effect of Flurbiprofen spray on postoperative tonsillectomy pain

Advanced Medical Journal, 2023
Background and objectives: Tonsillectomy is one of the most frequently performed surgical procedures. Up to date there are no guidelines for pain control following tonsillectomy.
Abdulkhaliq Kerim Hamad Emin
doaj   +1 more source

Beeswax: Food and beyond

Food Biomacromolecules, EarlyView.
Abstract Honeybees (Apis mellifera L.) are an important class of insects that are the most beneficial in terms of economy. Beeswax is the second most important bee products after honey. Its commercial importance is due to its antimicrobial, antioxidant, anti‐inflammatory and antiseptic as well as regenerative properties.
Rajshri Naveen, Manickam Loganathan
wiley   +1 more source

A model‐based analysis of the CYP2C9 genotype effects on fluconazole inhibition using flurbiprofen, ketoprofen and tolbutamide as probe drugs

British Journal of Pharmacology, EarlyView.
Background The activity of CYP2C9, an important drug metabolism enzyme, is subject to the impact of genetic polymorphism. The single nucleotide polymorphism *3 is significantly associated with the increased exposure of CYP2C9 substrates. In addition, metabolic enzyme inhibitors such as fluconazole may also increase the drug exposure of CYP2C9 ...
Shen Cheng, Darcy R. Flora, Mutaz M. Jaber, Allan E. Rettie, Richard C. Brundage, Timothy S. Tracy   +5 more
wiley   +1 more source

Soft‐Tissue Phenotype Modification as an Adjunct to the Treatment of Peri‐Implant Mucositis—A Quasi‐Randomized Clinical Trial

Journal of Periodontal Research, EarlyView.
This study showed that soft‐tissue phenotype modification provides additional benefits beyond non‐surgical therapy in managing peri‐implant mucositis. Notably, the effects on peri‐implant health were not mediated by improved plaque control. ABSTRACT Aim This quasi‐randomized clinical trial evaluated the additional benefit of soft‐tissue phenotype ...
Zeynep Aksu, Sila Cagri Isler, Berrin Unsal, Andrea Roccuzzo, Mario Romandini   +4 more
wiley   +1 more source

Association between perioperative flurbiprofen administration and acute kidney injury (AKI) in spine surgery: a retrospective cohort study

Perioperative Medicine
Background The association between nonsteroidal anti-inflammatory drugs (NSAIDs) and postoperative acute kidney injury (AKI) remains controversial, with limited studies specifically examining flurbiprofen.
Yongrong Liu, Bo Li, Lihua Hang, Li Zhang   +3 more
doaj   +1 more source

Stability-indicating RP-HPLC method for simultaneous determination of gatifloxacin and flurbiprofen in binary combination

Química Nova, 2014
A stability-indicating RP-HPLC method is presented for determination of gatifloxacin and flurbiprofen in binary combination. Gatifloxacin, flurbiprofen and their degradation products were detected at 254 nm using a BDS Hypersil C8 (250 X 4.6 mm, 5 µm ...
Islam Ullah Khan, Syed Naeem Razzaq, Irfana Mariam, Muhammad Ashfaq, Syed Saleem Razzaq   +4 more
doaj   +1 more source

Matrix Metalloproteinases in Periodontal and Peri‐Implant Diseases: Contribution to Their Pathogenesis, Diagnosis, and Treatment

Journal of Periodontal Research, EarlyView.
This graphical abstract illustrates the role of matrix metalloproteinases (MMPs) across the pathogenesis, diagnosis, and therapeutics of periodontal and peri‐implant diseases. Microbial and host stimuli trigger MMP activation leading to extracellular matrix breakdown, point‐of‐care aMMP‐8 detection aids diagnosis, and adjunctive or AI‐assisted ...
Timo Sorsa, Lorne M. Golub, Julie Toby Thomas, Pietro Leone, Sukumaran Anil, Veli‐Jukka Uitto   +5 more
wiley   +1 more source

R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids.

PLoS ONE, 2010
BackgroundR-flurbiprofen, one of the enantiomers of flurbiprofen racemate, is inactive with respect to cyclooxygenase inhibition, but shows analgesic properties without relevant toxicity.
Philipp Bishay, Helmut Schmidt, Claudiu Marian, Annett Häussler, Nina Wijnvoord, Simone Ziebell, Julia Metzner, Marco Koch, Thekla Myrczek, Ingo Bechmann, Rohini Kuner, Michael Costigan, Faramarz Dehghani, Gerd Geisslinger, Irmgard Tegeder   +14 more
doaj   +1 more source

Emerging locally delivered antimicrobial and immunomodulatory approaches for the prevention/treatment of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje, Ettore Amerio, Irene Mallor, Conrado Aparicio   +3 more
wiley   +1 more source