Results 51 to 60 of about 6,780 (162)
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
Inhibition of endocannabinoid metabolism by the metabolites of ibuprofen and flurbiprofen.
BackgroundIn addition to their effects upon prostaglandin synthesis, the non-steroidal anti-inflammatory drugs ibuprofen and flurbiprofen inhibit the metabolism of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA) by cyclooxygenase ...
Jessica Karlsson, Christopher J Fowler
doaj +1 more source
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao +13 more
wiley +1 more source
ABSTRACT There is limited information regarding the contemporary real‐world clinical and financial burden of Medicaid enrollees with sickle cell disease (SCD) in the United States. Using the IBM MarketScan Medicaid database (7/2016–12/2020), individuals with ≥ 3 SCD diagnoses were matched 1:1 on age, gender, and race to individuals without SCD ...
Giovanna Tedesco Barcelos +4 more
wiley +1 more source
Jingru Zhang,1,2,* Hong Zhang,1,* Libo Zhao,3 Jian Gu,4 Yi Feng,1 Haiyan An1 1Department of Anesthesiology, Peking University People’s Hospital, Beijing 100044, China; 2Department of Pharmacy Administration and Clinical Pharmacy, School of ...
Zhang J +5 more
doaj
Endoplasmic reticulum (ER) stress, caused by the accumulation of unfolded proteins, is involved in the development of obesity. We demonstrated that flurbiprofen, a nonsteroidal anti‐inflammatory drug (NSAID), exhibited chaperone activity, which reduced ...
Toru Hosoi +9 more
doaj +1 more source
ABSTRACT The analysis of interactions between biological agents or with surrounding chemicals is important in many areas of modern biochemical, biomedical, and environmental research. Microscale platforms based on affinity chromatography have been shown to be a powerful set of tools for these studies.
David S. Hage +8 more
wiley +1 more source
Effect of flurbiprofen sodium on pupillary dilatation during scleral buckling surgery
Maintenance of pupillary dilatation is necessary for success of scleral buckling procedures. The efficacy of 0.03% flurbiprofen in preventing intraoperative miosis was evaluated by a prospective randomized, double-masked controlled trial of 60 ...
Roysarkar T +4 more
doaj
Flurbiprofen ameliorates glucose deprivation-induced leptin resistance
Leptin resistance is one of the mechanisms involved in the pathophysiology of obesity. The present study showed that glucose deprivation inhibited leptin-induced phosphorylation of signal transducer and activator of transcription 3 (STAT3) and signal ...
Toru Hosoi +3 more
doaj +1 more source
A simple, rapid, sensitive, and specific high-performance liquid chromatography (HPLC) assay for flurbiprofen has been developed and validated practically.
Muhammad Akhlaq +6 more
doaj +1 more source

