Effect of flurbiprofen axetil on postoperative delirium for elderly patients [PDF]
Brain and Behavior, 2019 Objectives Proinflammatory cytokines triggered by surgery and postoperative pain are major causes of postoperative delirium (POD). This study investigated the effects of flurbiprofen axetil on POD when used for postoperative analgesia after major ...
Xifan Wang +7 more
doaj +5 more sources
Efficacy of flurbiprofen axetil for preventing postanesthetic shivering in patients undergoing gynecologic laparotomy surgeries [PDF]
JA Clinical Reports, 2020 Background Postanesthetic shivering is an unpleasant adverse event in surgical patients. A nonsteroidal anti-inflammatory drug has been reported to be useful in preventing postanesthetic shivering in several previous studies. The aim of this study was to
Atsushi Kotera
doaj +5 more sources
The Comparison of Plasma and Cerebrospinal Fluid R(−)- and S(+)-Flurbiprofen Concentration After Intravenous Injection of Flurbiprofen Axetil in Human Subjects [PDF]
Frontiers in Pharmacology, 2021 Background: Flurbiprofen axetil is a prodrug that releases the active substance through enzymatic removal of the ester moiety. It is formulated through encapsulation in a lipid microsphere carrier, and widely used to treat perioperative pain.
Han Yao +5 more
doaj +5 more sources
Long-Circulating Lipid Nanospheres Loaded with Flurbiprofen Axetil for Targeted Rheumatoid Arthritis Treatment [PDF]
International Journal of Nanomedicine, 2023 Zhenyu Chen,1,2,* Zhongbing Liu,1,* Shuzao Wang,1,* Cai Cheng,1,* Xiaoduan Sun,1 Zerong Liu,3 Jun Wei,1 Jun Jiang,4,5 Huaqi Lan,1 Meiling Zhou,6 Pei Jing,6 Yan Lin,1 Xiangyu Zhou,7 Zhirong Zhong1,3,8 1Key Laboratory of Medical ...
Chen Z +13 more
doaj +4 more sources
Therapeutic effects of flurbiprofen axetil on mesenteric traction syndrome: randomized clinical trial [PDF]
BMC Surgery, 2017 Background This study aimed to reveal the appropriate timing for the intravenous administration of flurbiprofen axetil for preventing mesenteric traction syndrome (MTS), caused by prostacyclin release.
Hidemasa Takahashi +6 more
doaj +5 more sources
Population pharmacokinetic modeling of flurbiprofen, the active metabolite of flurbiprofen axetil, in Chinese patients with postoperative pain [PDF]
Journal of Pain Research, 2018 Jingru Zhang,1,2,* Hong Zhang,1,* Libo Zhao,3 Jian Gu,4 Yi Feng,1 Haiyan An1 1Department of Anesthesiology, Peking University People’s Hospital, Beijing 100044, China; 2Department of Pharmacy Administration and Clinical Pharmacy, School of ...
Zhang J +5 more
doaj +5 more sources
Population Pharmacokinetic Modeling Of Flurbiprofen, The Active Metabolite Of Flurbiprofen Axetil, In Chinese Patients With Postoperative Pain [Expression Of Concern] [PDF]
Journal of Pain Research, 2019 Zhang J, Zhang H, Zhao L, Gu J, Feng Y, An H. Population pharmacokinetic modeling of flurbiprofen, the active metabolite of flurbiprofen axetil, in Chinese patients with postoperative pain. J Pain Res. 2018;11:3061–3070.The Editor-in-
Zhang J +5 more
doaj +5 more sources
Efficacy and safety of parecoxib and flurbiprofen axetil for perioperative analgesia in children: a network meta-analysis [PDF]
Frontiers in Medicine, 2023 ObjectiveThe aim of this study was to systematically review the efficacy and safety of parecoxib and flurbiprofen axetil for perioperative analgesia in children through Bayesian network meta-analysis.MethodsWe systematically searched PubMed, Embase ...
Xi Chen +6 more
doaj +2 more sources
Effect of Lung Protective Ventilation Combined With Flurbiprofen Axetil on Immune Function During Thoracoscopic Radical Resection of Lung Cancer [PDF]
Frontiers in Surgery, 2022 The decreased immune function of patients with lung cancer has always been the focus of clinical attention. However, the stress response caused by surgery, anesthesia and pain will further reduce the body's immune function and affect the prognosis of ...
Jia Yuan +6 more
doaj +2 more sources
Intravenous flurbiprofen axetil can increase analgesic effect in refractory cancer pain [PDF]
Journal of Experimental & Clinical Cancer Research, 2009 Background The aim of this study was to investigate the analgesic effects of intravenous flurbiprofen axetil for the refractory pain in cancer patients.
Hao Jiqing +7 more
doaj +3 more sources